Portal-systemic shunt with cerebellar ataxia as the initial neurological manifestation which was dramatically improved by an intravenous administration of branched amino acid

Kentaro Deguchi, Yasuhiro Manabe, Koji Takahashi, Taisei Ota, Kazuhiro Takamatsu, Kentaro Ida, Kosuke Ota, Koji Abe

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 58-year-old woman began to show ataxia at age 45 and dysarthria at age 56. Neurological examination revealed slurred speech, truncal ataxia, and pyramydal sign. Neither history of alcoholism nor hereditary factors were found. The level of serum ammonia was increased. Brain MRI study showed a high signal intensity in the cerebral peduncle and globus pallidus and mild cerebellar atrophy on T 1-weighted image. A portal-systemic shunt due to a shunt vessel was found between the left splenic and kidney veins although she did not show any other symptoms or signs due to liver cirrhosis. Her symptoms dramatically improved by an intravenous administration of branched amino acid. The present case suggests an importance in finding a treatable cerebellar ataxia.

Original languageEnglish
Pages (from-to)35-40
Number of pages6
JournalBrain and Nerve
Volume54
Issue number1
Publication statusPublished - 2002

Fingerprint

Cerebellar Ataxia
Ataxia
Neurologic Manifestations
Intravenous Administration
Splenic Vein
Amino Acids
Dysarthria
Globus Pallidus
Neurologic Examination
Ammonia
Liver Cirrhosis
Alcoholism
Signs and Symptoms
Atrophy
Kidney
Brain
Serum
Cerebral Peduncle

Keywords

  • Cerebellar ataxia
  • Hepatic encephalopathy
  • Portal-systemic shunt

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Portal-systemic shunt with cerebellar ataxia as the initial neurological manifestation which was dramatically improved by an intravenous administration of branched amino acid. / Deguchi, Kentaro; Manabe, Yasuhiro; Takahashi, Koji; Ota, Taisei; Takamatsu, Kazuhiro; Ida, Kentaro; Ota, Kosuke; Abe, Koji.

In: Brain and Nerve, Vol. 54, No. 1, 2002, p. 35-40.

Research output: Contribution to journalArticle

Deguchi, Kentaro ; Manabe, Yasuhiro ; Takahashi, Koji ; Ota, Taisei ; Takamatsu, Kazuhiro ; Ida, Kentaro ; Ota, Kosuke ; Abe, Koji. / Portal-systemic shunt with cerebellar ataxia as the initial neurological manifestation which was dramatically improved by an intravenous administration of branched amino acid. In: Brain and Nerve. 2002 ; Vol. 54, No. 1. pp. 35-40.
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