Polycythemia vera diagnosed after esophageal variceal rupture

Yoshiyasu Kono, Akinobu Takaki, Hideo Gobara, Ken-ichi Matsuoka, Masato Nishino, Hiroyuki Okada, Kazuhide Yamamoto

Research output: Contribution to journalArticle

Abstract

Polycythemia vera (PV) is a chronic myeloproliferative neoplasm that leads to hyperviscosity and the risk of thrombosis. We encountered the case of a young male Filipino patient diagnosed with PV after the rupture of esophageal varices. The complete blood cell count showed a slight increase in white blood cells. An abdominal computed tomography scan disclosed splenomegaly and occlusion of the portal vein and collateral vessels. A blood examination demonstrated an increase in all three blood cell lines within three months. Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.

Original languageEnglish
Pages (from-to)2395-2399
Number of pages5
JournalInternal Medicine
Volume54
Issue number18
DOIs
Publication statusPublished - Sep 15 2015

Fingerprint

Polycythemia Vera
Rupture
Blood Cell Count
Esophageal and Gastric Varices
Splenomegaly
Portal Vein
Blood Cells
Thrombosis
Leukocytes
Bone Marrow
Tomography
Cell Line
Mutation
Neoplasms

Keywords

  • Esophagogastric varices
  • Polycythemia vera (PV)
  • Portal hypertension
  • Thrombosis

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Polycythemia vera diagnosed after esophageal variceal rupture. / Kono, Yoshiyasu; Takaki, Akinobu; Gobara, Hideo; Matsuoka, Ken-ichi; Nishino, Masato; Okada, Hiroyuki; Yamamoto, Kazuhide.

In: Internal Medicine, Vol. 54, No. 18, 15.09.2015, p. 2395-2399.

Research output: Contribution to journalArticle

Kono, Yoshiyasu ; Takaki, Akinobu ; Gobara, Hideo ; Matsuoka, Ken-ichi ; Nishino, Masato ; Okada, Hiroyuki ; Yamamoto, Kazuhide. / Polycythemia vera diagnosed after esophageal variceal rupture. In: Internal Medicine. 2015 ; Vol. 54, No. 18. pp. 2395-2399.
@article{24d445bbd53740a0a5e7f908ee19298c,
title = "Polycythemia vera diagnosed after esophageal variceal rupture",
abstract = "Polycythemia vera (PV) is a chronic myeloproliferative neoplasm that leads to hyperviscosity and the risk of thrombosis. We encountered the case of a young male Filipino patient diagnosed with PV after the rupture of esophageal varices. The complete blood cell count showed a slight increase in white blood cells. An abdominal computed tomography scan disclosed splenomegaly and occlusion of the portal vein and collateral vessels. A blood examination demonstrated an increase in all three blood cell lines within three months. Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.",
keywords = "Esophagogastric varices, Polycythemia vera (PV), Portal hypertension, Thrombosis",
author = "Yoshiyasu Kono and Akinobu Takaki and Hideo Gobara and Ken-ichi Matsuoka and Masato Nishino and Hiroyuki Okada and Kazuhide Yamamoto",
year = "2015",
month = "9",
day = "15",
doi = "10.2169/internalmedicine.54.4687",
language = "English",
volume = "54",
pages = "2395--2399",
journal = "Internal Medicine",
issn = "0918-2918",
publisher = "Japanese Society of Internal Medicine",
number = "18",

}

TY - JOUR

T1 - Polycythemia vera diagnosed after esophageal variceal rupture

AU - Kono, Yoshiyasu

AU - Takaki, Akinobu

AU - Gobara, Hideo

AU - Matsuoka, Ken-ichi

AU - Nishino, Masato

AU - Okada, Hiroyuki

AU - Yamamoto, Kazuhide

PY - 2015/9/15

Y1 - 2015/9/15

N2 - Polycythemia vera (PV) is a chronic myeloproliferative neoplasm that leads to hyperviscosity and the risk of thrombosis. We encountered the case of a young male Filipino patient diagnosed with PV after the rupture of esophageal varices. The complete blood cell count showed a slight increase in white blood cells. An abdominal computed tomography scan disclosed splenomegaly and occlusion of the portal vein and collateral vessels. A blood examination demonstrated an increase in all three blood cell lines within three months. Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.

AB - Polycythemia vera (PV) is a chronic myeloproliferative neoplasm that leads to hyperviscosity and the risk of thrombosis. We encountered the case of a young male Filipino patient diagnosed with PV after the rupture of esophageal varices. The complete blood cell count showed a slight increase in white blood cells. An abdominal computed tomography scan disclosed splenomegaly and occlusion of the portal vein and collateral vessels. A blood examination demonstrated an increase in all three blood cell lines within three months. Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.

KW - Esophagogastric varices

KW - Polycythemia vera (PV)

KW - Portal hypertension

KW - Thrombosis

UR - http://www.scopus.com/inward/record.url?scp=84941595479&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84941595479&partnerID=8YFLogxK

U2 - 10.2169/internalmedicine.54.4687

DO - 10.2169/internalmedicine.54.4687

M3 - Article

VL - 54

SP - 2395

EP - 2399

JO - Internal Medicine

JF - Internal Medicine

SN - 0918-2918

IS - 18

ER -