Polycyclic N‐heterocyclic compounds. XLV. Synthesis of 4‐substituted 5,6‐dihydrobenzo[h]quinazolines and 6,7‐dihydro‐5H‐benzo[6,7]cyclohepta[1,2‐d]pyrimidines and their inhibitory activity on platelet aggregation

Kenji Sasaki, Yuhki Sekiya, Hideko Fujiwara, Hiromi Ohtomo, Taiji Nakayama, Takashi Hirota

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Abstract

The synthesis of 4‐substituted 5,6‐dihydrobenzo[h]quinazolines and 6,7‐dihydro‐5H‐benzo[6,7]cyclohepta‐[1,2‐d]pyrimidines with substituents which are an electron‐attracting group such as a nitrite, an amide, a thione, or a carboxyl group is described. Their inhibitory activity against collagen‐induced platelet aggregation was also investigated.

Original languageEnglish
Pages (from-to)993-995
Number of pages3
JournalJournal of Heterocyclic Chemistry
Volume30
Issue number4
DOIs
Publication statusPublished - Jan 1 1993

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ASJC Scopus subject areas

  • Organic Chemistry

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