Abstract
A simple and highly efficient methodology for the synthesis of 1,2,4,5‐tetrahydro[1]benzothiepino[4,5‐e]‐imidazo[1,2‐c]pyrimidine (XI) having a novel ring system via 4‐substituted 5,6‐dihydro[1]benzothiepino‐[5,4‐d]pyrimidines VII‐X is described. The anti‐platelet aggregation activity for it and its related compounds against collagen‐induced aggregation of rabbit blood platelets in vitro was found.
| Original language | English |
|---|---|
| Pages (from-to) | 513-515 |
| Number of pages | 3 |
| Journal | Journal of Heterocyclic Chemistry |
| Volume | 28 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Jan 1 1991 |
ASJC Scopus subject areas
- Organic Chemistry
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Nagamatsu, T., Kinoshita, K., Sasaki, K., Nakayama, T., & Hirota, T. (1991). Polycyclic N‐hetero compounds. XXXVII. A convenient synthesis and evaluation of anti‐platelet aggregation activity of 1,2,4,5‐tetrahydro[1]‐ benzothiepino[4,5‐e]imidazo[1,2‐c]pyrimidine and its related compounds. Journal of Heterocyclic Chemistry, 28(2), 513-515. https://doi.org/10.1002/jhet.5570280260