Polycyclic N‐hetero compounds. XXXIII. Syntheses of 4‐substituted 6,7‐dihydro‐5H‐benzo[6,7]‐cyclohepta[1,2‐d]pyrimidines and their inhibitory activities on platelet aggregation and on reserpine‐induced hypothermia

Kenji Sasaki, Takashi Hirota, Yuichi Arimoto, Yoshiko Satoh, Hiromi Ohtomo, Taiji Nakayama

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Various 4‐substituted 6,7‐dihydro‐5H‐benzo[6,7]cyclohepta[1,2‐d]pyrimidines were synthesized by the reaction of 4‐chloro‐6,7‐dihydro‐5H‐benzo[6,7]cyclohepta[1,2‐d]pyrimidine with amines. Their inhibitory activities against collagen‐induced platelet aggregation and also against reserpine‐induced hypothermia in mice were investigated.

Original languageEnglish
Pages (from-to)1771-1776
Number of pages6
JournalJournal of Heterocyclic Chemistry
Volume27
Issue number6
DOIs
Publication statusPublished - Jan 1 1990

ASJC Scopus subject areas

  • Organic Chemistry

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