Polycyclic N‐hetero compounds. XXVII. Synthesis and investigation of the antidepressive activity of a B‐Homo‐11,13,15‐triazasteroid and its related compoundsd

Takashi Hirota, Katsuhiro Ieno, Kenji Sasaki

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18 Citations (Scopus)

Abstract

A synthesis of 1,2,5,6‐tetrahydro‐4H‐benzo[3,4]cyclohepta[1,2‐e]imidazo[1,2‐c]pyrimidine (XII) having a novel ring system is described. Antidepressive activity of XII and its precursors VII‐X was screened by inhibitory action of reserpine‐induced hypothermia.

Original languageEnglish
Pages (from-to)1685-1687
Number of pages3
JournalJournal of Heterocyclic Chemistry
Volume23
Issue number6
DOIs
Publication statusPublished - Jan 1 1986

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ASJC Scopus subject areas

  • Organic Chemistry

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