Abstract
Syntheses of novel 15‐thia‐11,13‐diazasteroidal skeleton IV and its D‐homo analogues are described. Meso‐ionic derivatives of IV were also synthesized. Antidepressive activities of these compounds and their precursors were screened. D‐Dihomothiadiazasteroid IX and 3,4,5,6‐tetrahydrobenzo[h]quinazoline‐4‐thione (V) exhibited antireserpine action.
| Original language | English |
|---|---|
| Pages (from-to) | 341-344 |
| Number of pages | 4 |
| Journal | Journal of Heterocyclic Chemistry |
| Volume | 24 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Jan 1 1987 |
ASJC Scopus subject areas
- Organic Chemistry
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Hirota, T., Hamazaki, R., Ohdoi, T., Sasaki, K., & Namba, T. (1987). Polycyclic N‐hetero compounds. XXIX. Synthesis and antidepressive evaluation of 15‐thia‐11,13‐diazasteroidal analogues and their precursors. Journal of Heterocyclic Chemistry, 24(2), 341-344. https://doi.org/10.1002/jhet.5570240209