Abstract
Syntheses of novel 15‐thia‐11,13‐diazasteroidal skeleton IV and its D‐homo analogues are described. Meso‐ionic derivatives of IV were also synthesized. Antidepressive activities of these compounds and their precursors were screened. D‐Dihomothiadiazasteroid IX and 3,4,5,6‐tetrahydrobenzo[h]quinazoline‐4‐thione (V) exhibited antireserpine action.
| Original language | English |
|---|---|
| Pages (from-to) | 341-344 |
| Number of pages | 4 |
| Journal | Journal of Heterocyclic Chemistry |
| Volume | 24 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1987 |
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ASJC Scopus subject areas
- Organic Chemistry
Cite this
Polycyclic N‐hetero compounds. XXIX. Synthesis and antidepressive evaluation of 15‐thia‐11,13‐diazasteroidal analogues and their precursors. / Hirota, Takashi; Hamazaki, Rieko; Ohdoi, Takako; Sasaki, Kenji; Namba, Tetsuto.
In: Journal of Heterocyclic Chemistry, Vol. 24, No. 2, 1987, p. 341-344.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Polycyclic N‐hetero compounds. XXIX. Synthesis and antidepressive evaluation of 15‐thia‐11,13‐diazasteroidal analogues and their precursors
AU - Hirota, Takashi
AU - Hamazaki, Rieko
AU - Ohdoi, Takako
AU - Sasaki, Kenji
AU - Namba, Tetsuto
PY - 1987
Y1 - 1987
N2 - Syntheses of novel 15‐thia‐11,13‐diazasteroidal skeleton IV and its D‐homo analogues are described. Meso‐ionic derivatives of IV were also synthesized. Antidepressive activities of these compounds and their precursors were screened. D‐Dihomothiadiazasteroid IX and 3,4,5,6‐tetrahydrobenzo[h]quinazoline‐4‐thione (V) exhibited antireserpine action.
AB - Syntheses of novel 15‐thia‐11,13‐diazasteroidal skeleton IV and its D‐homo analogues are described. Meso‐ionic derivatives of IV were also synthesized. Antidepressive activities of these compounds and their precursors were screened. D‐Dihomothiadiazasteroid IX and 3,4,5,6‐tetrahydrobenzo[h]quinazoline‐4‐thione (V) exhibited antireserpine action.
UR - http://www.scopus.com/inward/record.url?scp=0023240884&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023240884&partnerID=8YFLogxK
U2 - 10.1002/jhet.5570240209
DO - 10.1002/jhet.5570240209
M3 - Article
VL - 24
SP - 341
EP - 344
JO - Journal of Heterocyclic Chemistry
JF - Journal of Heterocyclic Chemistry
SN - 0022-152X
IS - 2
ER -