Polycyclic N‐hetero compounds. XXIX. Synthesis and antidepressive evaluation of 15‐thia‐11,13‐diazasteroidal analogues and their precursors

Takashi Hirota, Rieko Hamazaki, Takako Ohdoi, Kenji Sasaki, Tetsuto Namba

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Syntheses of novel 15‐thia‐11,13‐diazasteroidal skeleton IV and its D‐homo analogues are described. Meso‐ionic derivatives of IV were also synthesized. Antidepressive activities of these compounds and their precursors were screened. D‐Dihomothiadiazasteroid IX and 3,4,5,6‐tetrahydrobenzo[h]quinazoline‐4‐thione (V) exhibited antireserpine action.

Original languageEnglish
Pages (from-to)341-344
Number of pages4
JournalJournal of Heterocyclic Chemistry
Volume24
Issue number2
DOIs
Publication statusPublished - Jan 1 1987

ASJC Scopus subject areas

  • Organic Chemistry

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