Polycyclic N‐hetero compounds. XXII Reaction of pyridine N‐oxides and Pyrazine di‐N‐oxides with formamide

Takashi Hirota, Tetsuto Namba, Kenji Sasaki

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Reactions of pyridine N‐oxides, pyrazine di‐N‐oxides, and their benzologues with formamide are described. Carbamoylation mainly occurred at aromatic ring with loss of the N‐oxide oxygen atom, however, 2,4,6‐trimethylpyridine 1‐oxide gave 2‐ and 4‐pyrimidinyl derivatives.

Original languageEnglish
Pages (from-to)949-953
Number of pages5
JournalJournal of Heterocyclic Chemistry
Issue number4
Publication statusPublished - 1987


ASJC Scopus subject areas

  • Organic Chemistry

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