Abstract
Reaction of 3-(3-cyanopropoxy)[1]benzofuran-2-carbonitriles with potassium tert-butoxide gave 5-amino-1,2-dihydro[1]benzofuro[3,2-d]furo[2,3-b]pyridines and 5-amino-2,3-dihydro[1]benzofuro[3,2-b]oxepin-4-carbonitriles as new ring systems. Reactions of the 5-chloro derivative, obtained from 5-amino-1,2-dihydro[1]benzofuro[3,2-d]furo[2,3-b]pyridine, produced a dihydrofuran ring-opened compound and 5-substituted compounds.
| Original language | English |
|---|---|
| Pages (from-to) | 281-287 |
| Number of pages | 7 |
| Journal | Journal of Heterocyclic Chemistry |
| Volume | 49 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Mar 1 2012 |
ASJC Scopus subject areas
- Organic Chemistry
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Cite this
Okuda, K., Takano, J. I., Hirota, T., & Sasaki, K. (2012). Polycyclic N-heterocyclic compounds, part 69: Synthesis of 5-amino-1,2-dihydro[1]benzofuro[3,2-d]furo[2,3-b]pyridines and their transformations to related compounds. Journal of Heterocyclic Chemistry, 49(2), 281-287. https://doi.org/10.1002/jhet.772