Polycyclic N-heterocyclic compounds, part 69: Synthesis of 5-amino-1,2-dihydro[1]benzofuro[3,2-d]furo[2,3-b]pyridines and their transformations to related compounds

Kensuke Okuda, Jun Ichi Takano, Takashi Hirota, Kenji Sasaki

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Reaction of 3-(3-cyanopropoxy)[1]benzofuran-2-carbonitriles with potassium tert-butoxide gave 5-amino-1,2-dihydro[1]benzofuro[3,2-d]furo[2,3-b]pyridines and 5-amino-2,3-dihydro[1]benzofuro[3,2-b]oxepin-4-carbonitriles as new ring systems. Reactions of the 5-chloro derivative, obtained from 5-amino-1,2-dihydro[1]benzofuro[3,2-d]furo[2,3-b]pyridine, produced a dihydrofuran ring-opened compound and 5-substituted compounds.

Original languageEnglish
Pages (from-to)281-287
Number of pages7
JournalJournal of Heterocyclic Chemistry
Volume49
Issue number2
DOIs
Publication statusPublished - Mar 1 2012

ASJC Scopus subject areas

  • Organic Chemistry

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