The versatile, one-step synthesis of imidazo[1,5-a]pyridines by the reaction of pyridine-2-carbonitriles with DMF under Vilsmeier conditions is described. This reaction was applied to the syntheses of imidazo[1,5-a]quinolines from quinoline-2-carbonitriles, and of imidazo[5,1-a]isoquinolines from isoquinoline-1-carbonitriles.
|Number of pages||6|
|Journal||Journal of the Chemical Society - Perkin Transactions 1|
|Publication status||Published - Nov 21 1998|
ASJC Scopus subject areas