Polycyclic N-heterocyclic compounds. 47 Synthesis and evaluation of anti-platelet aggregation activity of 11,13,15-triazasteroid and related compounds

Kenji Sasaki, Tomohiro Funabashi, Hiromi Ohtomo, Taiji Nakayama, Takashi Hirota

    Research output: Contribution to journalArticlepeer-review

    7 Citations (Scopus)

    Abstract

    Synthesis and separation of cis- and trans-1,2,4,5,5a,6,7,8,9,9a-decahydrobenz[h]imidazo[1,2-c]quinazolines and its precursors are described. Inhibitory activity against collagen-induced platelet aggregation for rabbit blood of these compounds and their benzologues at A ring is also evaluated.

    Original languageEnglish
    Pages (from-to)2251-2262
    Number of pages12
    JournalHeterocycles
    Volume41
    Issue number10
    Publication statusPublished - Oct 1 1995

    ASJC Scopus subject areas

    • Analytical Chemistry
    • Pharmacology
    • Organic Chemistry

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