Polycyclic N-heterocyclic compounds. 47 Synthesis and evaluation of anti-platelet aggregation activity of 11,13,15-triazasteroid and related compounds

Kenji Sasaki, Tomohiro Funabashi, Hiromi Ohtomo, Taiji Nakayama, Takashi Hirota

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Synthesis and separation of cis- and trans-1,2,4,5,5a,6,7,8,9,9a-decahydrobenz[h]imidazo[1,2-c]quinazolines and its precursors are described. Inhibitory activity against collagen-induced platelet aggregation for rabbit blood of these compounds and their benzologues at A ring is also evaluated.

Original languageEnglish
Pages (from-to)2251-2262
Number of pages12
JournalHeterocycles
Volume41
Issue number10
Publication statusPublished - Oct 1 1995

Fingerprint

Quinazolines
Heterocyclic Compounds
Platelets
Platelet Aggregation
Blood
Collagen
Agglomeration
Rabbits

ASJC Scopus subject areas

  • Pharmacology
  • Organic Chemistry
  • Analytical Chemistry

Cite this

Polycyclic N-heterocyclic compounds. 47 Synthesis and evaluation of anti-platelet aggregation activity of 11,13,15-triazasteroid and related compounds. / Sasaki, Kenji; Funabashi, Tomohiro; Ohtomo, Hiromi; Nakayama, Taiji; Hirota, Takashi.

In: Heterocycles, Vol. 41, No. 10, 01.10.1995, p. 2251-2262.

Research output: Contribution to journalArticle

Sasaki, Kenji ; Funabashi, Tomohiro ; Ohtomo, Hiromi ; Nakayama, Taiji ; Hirota, Takashi. / Polycyclic N-heterocyclic compounds. 47 Synthesis and evaluation of anti-platelet aggregation activity of 11,13,15-triazasteroid and related compounds. In: Heterocycles. 1995 ; Vol. 41, No. 10. pp. 2251-2262.
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