Polycyclic N-hetero compounds. XXV. Synthesis of novel D-homo-11,13,15-triazasteroidal skeleton and investigation of its antidepressive activity

Takashi Hirota, Keiko Kawanishi, Kenji Sasaki

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A synthesis of D-homo-11,13,15-triazasteroidal skeleton, corresponding to benzo[h]pyrimido[1,2-c]quinazoline as a novel ring system is described. Antidepressive activity of these compounds was screened by inhibitory action of reserpine-induced hypothermia. Compounds VIIc and XVI exhibited antireserpine action.

Original languageEnglish
Pages (from-to)1119-1130
Number of pages12
JournalHeterocycles
Volume24
Issue number4
Publication statusPublished - Apr 1 1986

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Hypothermia
Quinazolines
Induced Hypothermia
Reserpine
Skeleton

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Polycyclic N-hetero compounds. XXV. Synthesis of novel D-homo-11,13,15-triazasteroidal skeleton and investigation of its antidepressive activity. / Hirota, Takashi; Kawanishi, Keiko; Sasaki, Kenji.

In: Heterocycles, Vol. 24, No. 4, 01.04.1986, p. 1119-1130.

Research output: Contribution to journalArticle

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