TY - JOUR
T1 - Polycyclic N-hetero compounds. XXI. Synthesis of novel ring system, 4H-imidazo [1′ 2′
T2 - 1,6]pyrimido [5,4-d][1]benzazepine as B-homo-6,11,13,15-tetraazasteroidal analogue
AU - Hirota, Takashi
AU - Fukumoto, Masami
AU - Sasaki, Kenji
AU - Namba, Tetsuto
AU - Hayakawa, Shohei
PY - 1986/1/1
Y1 - 1986/1/1
N2 - A synthesis of 4H-imidazo [1′,2′: 1,6]pyrimido-[5,4-d] [1]benzazepine (XIIIa) having a novel ring system is described. Methyl anthranilate (IVa) was converted to 4-(2-hydroxyethylamino)-6,7-dihydro-5H-pyrimido [5,4-d][1]-benzazepine (XIa) in several steps and XIa was cyclized to XIIIa. A synthesis of 8-chloro derivative of XIIIa is also described.
AB - A synthesis of 4H-imidazo [1′,2′: 1,6]pyrimido-[5,4-d] [1]benzazepine (XIIIa) having a novel ring system is described. Methyl anthranilate (IVa) was converted to 4-(2-hydroxyethylamino)-6,7-dihydro-5H-pyrimido [5,4-d][1]-benzazepine (XIa) in several steps and XIa was cyclized to XIIIa. A synthesis of 8-chloro derivative of XIIIa is also described.
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U2 - 10.3987/R-1986-01-0143
DO - 10.3987/R-1986-01-0143
M3 - Article
AN - SCOPUS:0013474909
VL - 24
SP - 143
EP - 154
JO - Heterocycles
JF - Heterocycles
SN - 0385-5414
IS - 1
ER -