Abstract
A synthesis of 4H-imidazo [1′,2′: 1,6]pyrimido-[5,4-d] [1]benzazepine (XIIIa) having a novel ring system is described. Methyl anthranilate (IVa) was converted to 4-(2-hydroxyethylamino)-6,7-dihydro-5H-pyrimido [5,4-d][1]-benzazepine (XIa) in several steps and XIa was cyclized to XIIIa. A synthesis of 8-chloro derivative of XIIIa is also described.
| Original language | English |
|---|---|
| Pages (from-to) | 143-154 |
| Number of pages | 12 |
| Journal | Heterocycles |
| Volume | 24 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 1 1986 |
ASJC Scopus subject areas
- Analytical Chemistry
- Pharmacology
- Organic Chemistry
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Cite this
Hirota, T., Fukumoto, M., Sasaki, K., Namba, T., & Hayakawa, S. (1986). Polycyclic N-hetero compounds. XXI. Synthesis of novel ring system, 4H-imidazo [1′ 2′: 1,6]pyrimido [5,4-d][1]benzazepine as B-homo-6,11,13,15-tetraazasteroidal analogue. Heterocycles, 24(1), 143-154. https://doi.org/10.3987/R-1986-01-0143