TY - JOUR
T1 - Polycyclic N-hetero compounds. XLII
T2 - Convenient syntheses of 6,7-dihydro-5H-pyrido[2,3-b]pyrimido[4,5-d]azepine as a novel polyheterocyclic ring system and its 4-substituted derivatives
AU - Nagamatsu, T.
AU - Hantani, Y.
AU - Takaishi, M.
AU - Sasaki, K.
AU - Hirota, T.
PY - 1991/1/1
Y1 - 1991/1/1
N2 - A convenient synthetic route for the syntheses of 6,7-dihydro-5H-pyrido[2,3-6]pyrimido[4,5-d]azepine and its 4-substituted derivatives starting from ethyl 2-aminopyridine-3-carboxylate is described as the fist example of the unknown ring system. A new class of anti-platelet aggregation activity for them against collagene-induced aggregation of rabbit blood platelet in vitro was found.
AB - A convenient synthetic route for the syntheses of 6,7-dihydro-5H-pyrido[2,3-6]pyrimido[4,5-d]azepine and its 4-substituted derivatives starting from ethyl 2-aminopyridine-3-carboxylate is described as the fist example of the unknown ring system. A new class of anti-platelet aggregation activity for them against collagene-induced aggregation of rabbit blood platelet in vitro was found.
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U2 - 10.1055/s-1991-26613
DO - 10.1055/s-1991-26613
M3 - Article
AN - SCOPUS:0025948461
SN - 0039-7881
SP - 942
EP - 946
JO - Synthesis
JF - Synthesis
IS - 11
ER -