Polyamines: Ubiquitous polycations with unique roles in growth and stress responses

Taku Takahashi, Jun Ichi Kakehi

Research output: Contribution to journalArticle

240 Citations (Scopus)

Abstract

Background Polyamines are small polycationic molecules found ubiquitously in all organisms and function in a wide variety of biological processes. In the past decade, molecular and genetic studies using mutants and transgenic plants with an altered activity of enzymes involved in polyamine biosynthesis have contributed much to a better understanding of the biological functions of polyamines in plants.Possible rolesSpermidine is essential for survival of Arabidopsis embryos. One of the reasons may lie in the fact that spermidine serves as a substrate for the lysine → hypusine post-translational modification of the eukaryotic translation initiation factor 5A, which is essential in all eukaryotic cells. Spermine is not essential but plays a role in stress responses, probably through the modulation of cation channel activities, and as a source of hydrogen peroxide during pathogen infection. Thermospermine, an isomer of spermine, is involved in stem elongation, possibly by acting on the regulation of upstream open reading frame-mediated translation. ConclusionsThe mechanisms of action of polyamines differ greatly from those of plant hormones. There remain numerous unanswered questions regarding polyamines in plants, such as transport systems and polyamine-responsive genes. Further studies on the action of polyamines will undoubtedly provide a new understanding of plant growth regulation and stress responses.

Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalAnnals of Botany
Volume105
Issue number1
DOIs
Publication statusPublished - Jan 2010

Fingerprint

polyamines
stress response
spermine
translation (genetics)
post-translational modification
spermidine
stem elongation
embryo (plant)
plant hormones
isomers
hydrogen peroxide
eukaryotic cells
open reading frames
transgenic plants
mechanism of action
cations
lysine
Arabidopsis
plant growth
biosynthesis

Keywords

  • ACL5
  • Polyamines
  • Putrescine
  • Spermidine
  • Spermine
  • Thermospermine
  • Translation
  • UORF

ASJC Scopus subject areas

  • Plant Science

Cite this

Polyamines : Ubiquitous polycations with unique roles in growth and stress responses. / Takahashi, Taku; Kakehi, Jun Ichi.

In: Annals of Botany, Vol. 105, No. 1, 01.2010, p. 1-6.

Research output: Contribution to journalArticle

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