Pneumatosis intestinalis after lung transplantation for pulmonary graft-versus-host disease

Research output: Contribution to journalArticle

Abstract

Pneumatosis intestinalis, which could complicate a spectrum of clinical conditions ranging from benign to life-threatening, is a rarely encountered complication after lung transplantation (LT). We describe two cases in which PI developed as a complication following LT for pulmonary graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation (HSCT). In addition to the long-term immunosuppression administered for pulmonary GVHD, the intense immunosuppression needed after LT might increase the risk of PI in lung transplant recipients after HSCT. Conservative therapy should be considered for the treatment of PI developing after LT.

Original languageEnglish
Pages (from-to)E42-E45
JournalJournal of Thoracic Disease
Volume10
Issue number1
DOIs
Publication statusPublished - Jan 1 2018

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Lung Transplantation
Graft vs Host Disease
Lung
Hematopoietic Stem Cell Transplantation
Immunosuppression
Therapeutics

Keywords

  • Complications
  • Computed tomography (CT)
  • Lung transplantation (LT)
  • Postoperative care

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

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abstract = "Pneumatosis intestinalis, which could complicate a spectrum of clinical conditions ranging from benign to life-threatening, is a rarely encountered complication after lung transplantation (LT). We describe two cases in which PI developed as a complication following LT for pulmonary graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation (HSCT). In addition to the long-term immunosuppression administered for pulmonary GVHD, the intense immunosuppression needed after LT might increase the risk of PI in lung transplant recipients after HSCT. Conservative therapy should be considered for the treatment of PI developing after LT.",
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author = "Kumi Mesaki and Seiichiro Sugimoto and Shinji Otani and Takeshi Kurosaki and Kentaroh Miyoshi and Masaomi Yamane and Takahiro Oto",
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AU - Mesaki, Kumi

AU - Sugimoto, Seiichiro

AU - Otani, Shinji

AU - Kurosaki, Takeshi

AU - Miyoshi, Kentaroh

AU - Yamane, Masaomi

AU - Oto, Takahiro

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N2 - Pneumatosis intestinalis, which could complicate a spectrum of clinical conditions ranging from benign to life-threatening, is a rarely encountered complication after lung transplantation (LT). We describe two cases in which PI developed as a complication following LT for pulmonary graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation (HSCT). In addition to the long-term immunosuppression administered for pulmonary GVHD, the intense immunosuppression needed after LT might increase the risk of PI in lung transplant recipients after HSCT. Conservative therapy should be considered for the treatment of PI developing after LT.

AB - Pneumatosis intestinalis, which could complicate a spectrum of clinical conditions ranging from benign to life-threatening, is a rarely encountered complication after lung transplantation (LT). We describe two cases in which PI developed as a complication following LT for pulmonary graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation (HSCT). In addition to the long-term immunosuppression administered for pulmonary GVHD, the intense immunosuppression needed after LT might increase the risk of PI in lung transplant recipients after HSCT. Conservative therapy should be considered for the treatment of PI developing after LT.

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KW - Lung transplantation (LT)

KW - Postoperative care

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