PNA arrays for miRNA detection

Tamaki Endoh, Mizuki Kitamatsu, Masahiko Sisido, Takashi Ohtsuki

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4 Citations (Scopus)

Abstract

The profiling of microRNAs (miRNAs) using microarray technology has been used in many recent biological and medical studies. In this study, arrays of peptide nucleic acids (PNAs) were prepared and their miRNA capture abilities were evaluated. We found that the sensitivity of 10-mer PNA probes in targeting miRNAs was much higher than that of the corresponding DNA probes and also of longer (20-mer) DNA probes.

Original languageEnglish
Pages (from-to)438-439
Number of pages2
JournalChemistry Letters
Volume38
Issue number5
DOIs
Publication statusPublished - 2009

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ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Endoh, T., Kitamatsu, M., Sisido, M., & Ohtsuki, T. (2009). PNA arrays for miRNA detection. Chemistry Letters, 38(5), 438-439. https://doi.org/10.1246/cl.2009.438