Platisidines A-C, N-methylpyridinium alkaloids from an okinawan marine sponge of Plakortis species

Takaaki Kubota, Yuichiro Ishiguro, Sunao Yamamoto, Jane Fromont, Jun'Ichi Kobayashi

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Three new N-methyl pyridinium alkaloids, platisidines A-C (13), were isolated from an Okinawan marine sponge of the genus Plakortis, and the structures were elucidated from spectroscopic data. The structures of platisidines A-C (13) were elucidated to be N-methyl nicotinic acid derivatives with a n-hexadecanoyl chain. Platisidines A-C (13) showed inhibitory activity against acetylcholinesterase.

Original languageEnglish
Pages (from-to)1407-1412
Number of pages6
JournalHeterocycles
Volume80
Issue number2
DOIs
Publication statusPublished - Mar 1 2010
Externally publishedYes

Keywords

  • Acetylcholinesterase Inhibitor
  • Plakortis species
  • Platisidines A-C
  • Pyridinium Alkaloid
  • Sponge

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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