Platelet Adhesion on Metal Oxide Layers

S. Takemoto, T. Yamamoto, K. Tsuru, Satoshi Hayakawa, A. Osaka

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

This study was concerned with blood compatibility of titanium oxide layers on stainless steel. The titanium oxide layers were prepared through sol-gel process by dip-coating of tetraethyltitanate solution and heated at 500°C. The crystal phase, thickness and wettability of the oxide were characterized. The blood compatibility was evaluated in term of platelet adhesion using human platelet rich plasma. Consequently, with increase in the thickness of the titanium oxide layers, the number of platelet adhered on the stainless steel coated with titanium oxide layer decreased rapidly, When the thickness of titanium oxide layers on stainless steel grew more than 150 nm, the number of adherent platelets decreased less than 10% in comparison with that on non-coated stainless steel. The titanium oxide layers indicated to be more hydrophilic than non-coated stainless steel. In conclusion, the thicker and more hydrophilic titanium oxide layer on stainless steel appears to inhibit platelet adhesion.

Original languageEnglish
Pages (from-to)853-856
Number of pages4
JournalKey Engineering Materials
Volume254-256
Publication statusPublished - 2004

Fingerprint

Titanium oxides
Platelets
Stainless Steel
Oxides
Adhesion
Metals
Stainless steel
Blood
titanium dioxide
Sol-gel process
Wetting
Plasmas
Coatings
Crystals

Keywords

  • Platelet adhesion
  • Sol-gel coating
  • Titanium oxide layer

ASJC Scopus subject areas

  • Ceramics and Composites
  • Chemical Engineering (miscellaneous)

Cite this

Takemoto, S., Yamamoto, T., Tsuru, K., Hayakawa, S., & Osaka, A. (2004). Platelet Adhesion on Metal Oxide Layers. Key Engineering Materials, 254-256, 853-856.

Platelet Adhesion on Metal Oxide Layers. / Takemoto, S.; Yamamoto, T.; Tsuru, K.; Hayakawa, Satoshi; Osaka, A.

In: Key Engineering Materials, Vol. 254-256, 2004, p. 853-856.

Research output: Contribution to journalArticle

Takemoto, S, Yamamoto, T, Tsuru, K, Hayakawa, S & Osaka, A 2004, 'Platelet Adhesion on Metal Oxide Layers', Key Engineering Materials, vol. 254-256, pp. 853-856.
Takemoto S, Yamamoto T, Tsuru K, Hayakawa S, Osaka A. Platelet Adhesion on Metal Oxide Layers. Key Engineering Materials. 2004;254-256:853-856.
Takemoto, S. ; Yamamoto, T. ; Tsuru, K. ; Hayakawa, Satoshi ; Osaka, A. / Platelet Adhesion on Metal Oxide Layers. In: Key Engineering Materials. 2004 ; Vol. 254-256. pp. 853-856.
@article{38ae7a86b11744f480cc4836b4de72b2,
title = "Platelet Adhesion on Metal Oxide Layers",
abstract = "This study was concerned with blood compatibility of titanium oxide layers on stainless steel. The titanium oxide layers were prepared through sol-gel process by dip-coating of tetraethyltitanate solution and heated at 500°C. The crystal phase, thickness and wettability of the oxide were characterized. The blood compatibility was evaluated in term of platelet adhesion using human platelet rich plasma. Consequently, with increase in the thickness of the titanium oxide layers, the number of platelet adhered on the stainless steel coated with titanium oxide layer decreased rapidly, When the thickness of titanium oxide layers on stainless steel grew more than 150 nm, the number of adherent platelets decreased less than 10{\%} in comparison with that on non-coated stainless steel. The titanium oxide layers indicated to be more hydrophilic than non-coated stainless steel. In conclusion, the thicker and more hydrophilic titanium oxide layer on stainless steel appears to inhibit platelet adhesion.",
keywords = "Platelet adhesion, Sol-gel coating, Titanium oxide layer",
author = "S. Takemoto and T. Yamamoto and K. Tsuru and Satoshi Hayakawa and A. Osaka",
year = "2004",
language = "English",
volume = "254-256",
pages = "853--856",
journal = "Key Engineering Materials",
issn = "1013-9826",
publisher = "Trans Tech Publications",

}

TY - JOUR

T1 - Platelet Adhesion on Metal Oxide Layers

AU - Takemoto, S.

AU - Yamamoto, T.

AU - Tsuru, K.

AU - Hayakawa, Satoshi

AU - Osaka, A.

PY - 2004

Y1 - 2004

N2 - This study was concerned with blood compatibility of titanium oxide layers on stainless steel. The titanium oxide layers were prepared through sol-gel process by dip-coating of tetraethyltitanate solution and heated at 500°C. The crystal phase, thickness and wettability of the oxide were characterized. The blood compatibility was evaluated in term of platelet adhesion using human platelet rich plasma. Consequently, with increase in the thickness of the titanium oxide layers, the number of platelet adhered on the stainless steel coated with titanium oxide layer decreased rapidly, When the thickness of titanium oxide layers on stainless steel grew more than 150 nm, the number of adherent platelets decreased less than 10% in comparison with that on non-coated stainless steel. The titanium oxide layers indicated to be more hydrophilic than non-coated stainless steel. In conclusion, the thicker and more hydrophilic titanium oxide layer on stainless steel appears to inhibit platelet adhesion.

AB - This study was concerned with blood compatibility of titanium oxide layers on stainless steel. The titanium oxide layers were prepared through sol-gel process by dip-coating of tetraethyltitanate solution and heated at 500°C. The crystal phase, thickness and wettability of the oxide were characterized. The blood compatibility was evaluated in term of platelet adhesion using human platelet rich plasma. Consequently, with increase in the thickness of the titanium oxide layers, the number of platelet adhered on the stainless steel coated with titanium oxide layer decreased rapidly, When the thickness of titanium oxide layers on stainless steel grew more than 150 nm, the number of adherent platelets decreased less than 10% in comparison with that on non-coated stainless steel. The titanium oxide layers indicated to be more hydrophilic than non-coated stainless steel. In conclusion, the thicker and more hydrophilic titanium oxide layer on stainless steel appears to inhibit platelet adhesion.

KW - Platelet adhesion

KW - Sol-gel coating

KW - Titanium oxide layer

UR - http://www.scopus.com/inward/record.url?scp=0347516119&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0347516119&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0347516119

VL - 254-256

SP - 853

EP - 856

JO - Key Engineering Materials

JF - Key Engineering Materials

SN - 1013-9826

ER -