Plastid proteases

Zach Adam, Wataru Sakamoto

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Steady-state levels of chloroplast proteins rely on the balance between synthesis and degradation rates. Thus, the importance of protein-degradation processes in shaping the chloroplast proteome, and hence proper organellar functioning, cannot be overestimated. Chloroplast proteases and peptidases participate in chloroplast biogenesis through maturation or activation of pre-proteins, adaptation to changing environmental conditions through degradation of certain proteins, and maintenance of protein quality through degradation of unassembled or damaged proteins. These activities are mediated by ATP-dependent and-independent proteases, many of which are encoded by multigene families. Newly imported proteins are processed by stroma- and thylakoid-localized peptidases that remove signal sequences, which are then further degraded. The multisubunit ATP-dependent Clp and FtsH complexes degrade housekeeping and oxidatively damaged proteins in the stroma and thylakoid membranes, respectively. A number of other chloroplast proteases have been identified, but their function and substrates are still unknown, as are the nature of degradation signals and determinants of protein instability. Future research is expected to focus on these questions.

Original languageEnglish
Title of host publicationPlastid Biology
PublisherSpringer New York
Pages359-389
Number of pages31
ISBN (Electronic)9781493911363
ISBN (Print)9781493911356
DOIs
Publication statusPublished - Jan 1 2014

Fingerprint

Plastids
plastids
Peptide Hydrolases
proteinases
Chloroplasts
chloroplasts
Thylakoids
Proteins
proteins
peptidases
Proteolysis
protein degradation
thylakoids
ATP-Dependent Proteases
degradation
Chloroplast Proteins
Housekeeping
Proteome
Multigene Family
Protein Sorting Signals

Keywords

  • Chaperones
  • Chloroplasts
  • Development
  • Proteases
  • Senescence
  • Thylakoids

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Adam, Z., & Sakamoto, W. (2014). Plastid proteases. In Plastid Biology (pp. 359-389). Springer New York. https://doi.org/10.1007/978-1-4939-1136-3_14

Plastid proteases. / Adam, Zach; Sakamoto, Wataru.

Plastid Biology. Springer New York, 2014. p. 359-389.

Research output: Chapter in Book/Report/Conference proceedingChapter

Adam, Z & Sakamoto, W 2014, Plastid proteases. in Plastid Biology. Springer New York, pp. 359-389. https://doi.org/10.1007/978-1-4939-1136-3_14
Adam Z, Sakamoto W. Plastid proteases. In Plastid Biology. Springer New York. 2014. p. 359-389 https://doi.org/10.1007/978-1-4939-1136-3_14
Adam, Zach ; Sakamoto, Wataru. / Plastid proteases. Plastid Biology. Springer New York, 2014. pp. 359-389
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