Pinopsin evolved as the ancestral dim-light visual opsin in vertebrates

Keita Sato, Takahiro Yamashita, Keiichi Kojima, Kazumi Sakai, Yuki Matsutani, Masataka Yanagawa, Yumiko Yamano, Akimori Wada, Naoyuki Iwabe, Hideyo Ohuchi, Yoshinori Shichida

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Pinopsin is the opsin most closely related to vertebrate visual pigments on the phylogenetic tree. This opsin has been discovered among many vertebrates, except mammals and teleosts, and was thought to exclusively function in their brain for extraocular photoreception. Here, we show the possibility that pinopsin also contributes to scotopic vision in some vertebrate species. Pinopsin is distributed in the retina of non-teleost fishes and frogs, especially in their rod photoreceptor cells, in addition to their brain. Moreover, the retinal chromophore of pinopsin exhibits a thermal isomerization rate considerably lower than those of cone visual pigments, but comparable to that of rhodopsin. Therefore, pinopsin can function as a rhodopsin-like visual pigment in the retinas of these lower vertebrates. Since pinopsin diversified before the branching of rhodopsin on the phylogenetic tree, two-step adaptation to scotopic vision would have occurred through the independent acquisition of pinopsin and rhodopsin by the vertebrate lineage.

Original languageEnglish
Article number156
JournalCommunications Biology
Volume1
Issue number1
DOIs
Publication statusPublished - Dec 1 2018

Fingerprint

Opsins
opsin
Rhodopsin
rhodopsin
Retinal Pigments
Vertebrates
vertebrates
Light
night vision
Night Vision
pigments
Brain
retina
Retina
Mammals
rods (retina)
Retinal Rod Photoreceptor Cells
brain
Chromophores
Isomerization

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • Medicine (miscellaneous)

Cite this

Pinopsin evolved as the ancestral dim-light visual opsin in vertebrates. / Sato, Keita; Yamashita, Takahiro; Kojima, Keiichi; Sakai, Kazumi; Matsutani, Yuki; Yanagawa, Masataka; Yamano, Yumiko; Wada, Akimori; Iwabe, Naoyuki; Ohuchi, Hideyo; Shichida, Yoshinori.

In: Communications Biology, Vol. 1, No. 1, 156, 01.12.2018.

Research output: Contribution to journalArticle

Sato, K, Yamashita, T, Kojima, K, Sakai, K, Matsutani, Y, Yanagawa, M, Yamano, Y, Wada, A, Iwabe, N, Ohuchi, H & Shichida, Y 2018, 'Pinopsin evolved as the ancestral dim-light visual opsin in vertebrates', Communications Biology, vol. 1, no. 1, 156. https://doi.org/10.1038/s42003-018-0164-x
Sato, Keita ; Yamashita, Takahiro ; Kojima, Keiichi ; Sakai, Kazumi ; Matsutani, Yuki ; Yanagawa, Masataka ; Yamano, Yumiko ; Wada, Akimori ; Iwabe, Naoyuki ; Ohuchi, Hideyo ; Shichida, Yoshinori. / Pinopsin evolved as the ancestral dim-light visual opsin in vertebrates. In: Communications Biology. 2018 ; Vol. 1, No. 1.
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