Pictet-spengler reaction using ion-exchange resin as a catalyst and support for 'catch and release' purification

Minoru IzuMi, Takeshi Kido, Miyu Murakami, Shuhei Nakajima, A. Ganesan

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

The Pictet-Spengler reaction between tryptamine and aldehydes was catalyzed by Dowex 50W-X4 acidic ion-exchange resin. The products were obtained from the resin in high purity by 'catch and release' without the need for separate chromatographic purification.

Original languageEnglish
Pages (from-to)391-392
Number of pages2
JournalBioscience, Biotechnology and Biochemistry
Volume75
Issue number2
DOIs
Publication statusPublished - 2011

Keywords

  • Alkaloid
  • Catch and release
  • Ion-exchange resin
  • Parallel synthesis
  • Pictet-spengler reaction

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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