"phosphite-urea" cooperative high-turnover catalysts for the highly selective bromocyclization of homogeranylarenes

Yasuhiro Sawamura, Hidefumi Nakatsuji, Akira Sakakura, Kazuaki Ishihara

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Nucleophilic phosphite-urea cooperative high-turnover catalysts have been designed for the highly selective bromocyclization of homogeranylarenes. The introduction of a urea moiety and bulky aryl groups in the catalyst inhibits decomposition of the catalyst and the generation of byproducts. Only 0.5 mol% of the catalyst successfully promotes the bromocyclization of 4-homogeranyltoluene to give the desired product in 96% yield.

Original languageEnglish
Pages (from-to)4181-4186
Number of pages6
JournalChemical Science
Volume4
Issue number11
DOIs
Publication statusPublished - 2013

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Phosphites
Urea
Catalysts
Byproducts
Decomposition

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

"phosphite-urea" cooperative high-turnover catalysts for the highly selective bromocyclization of homogeranylarenes. / Sawamura, Yasuhiro; Nakatsuji, Hidefumi; Sakakura, Akira; Ishihara, Kazuaki.

In: Chemical Science, Vol. 4, No. 11, 2013, p. 4181-4186.

Research output: Contribution to journalArticle

Sawamura, Yasuhiro ; Nakatsuji, Hidefumi ; Sakakura, Akira ; Ishihara, Kazuaki. / "phosphite-urea" cooperative high-turnover catalysts for the highly selective bromocyclization of homogeranylarenes. In: Chemical Science. 2013 ; Vol. 4, No. 11. pp. 4181-4186.
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