Peroxidase-like Catalytic Activity of Anion-Exchange Resins Modified with Metalloporphyrins in the Dye Formation Reaction of N, N-Diethylaniline with 4-Aminoantipyrine by Hydrogen Peroxide

Yutaka Saito; Masaki Mifune; Suzuyo Nakashima; Hiromi Nakayama; Junichi Odo; Yoshimasa Tanaka; Masahiko Chikuma; Hisashi Tanaka

doi:10.1248/cpb.35.869

Peroxidase-like Catalytic Activity of Anion-Exchange Resins Modified with Metalloporphyrins in the Dye Formation Reaction of N, N-Diethylaniline with 4-Aminoantipyrine by Hydrogen Peroxide

Yutaka Saito, Masaki Mifune, Suzuyo Nakashima, Hiromi Nakayama, Junichi Odo, Yoshimasa Tanaka, Masahiko Chikuma, Hisashi Tanaka

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

In an attempt to develop a practically useful mimesis of peroxidase, the peroxidase-like catalytic activity of anion exchange resins (Amberlite IRA 900) modified with manganese, cobalt, iron, copper and zinc complexes of some porphyrins was examined in terms of the accelerating effect on dye formation in the following reaction. The evaluation of the activity was carried out by comparison of the effect obtained by using the resins with that obtained by using peroxidase. peroxidase 4-aminoantipyrine+ N, N,-diethylaniline + 2H202 →Peroxidase quinoid dye + 4H20 Amberlite IRA 900 modified with manganese-tetrakis(sulfophenyl)porphine was found to be the best among the resins tested.

Original language	English
Pages (from-to)	869-872
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	35
Issue number	2
DOIs	https://doi.org/10.1248/cpb.35.869
Publication status	Published - 1987

Keywords

functionalization ion-exchange resin
peroxidase mimesis
peroxidase-like activity
quinoid dye formation
resin modified metalloporphyrin

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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10.1248/cpb.35.869

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Saito, Y., Mifune, M., Nakashima, S., Nakayama, H., Odo, J., Tanaka, Y., Chikuma, M., & Tanaka, H. (1987). Peroxidase-like Catalytic Activity of Anion-Exchange Resins Modified with Metalloporphyrins in the Dye Formation Reaction of N, N-Diethylaniline with 4-Aminoantipyrine by Hydrogen Peroxide. Chemical and Pharmaceutical Bulletin, 35(2), 869-872. https://doi.org/10.1248/cpb.35.869

Peroxidase-like Catalytic Activity of Anion-Exchange Resins Modified with Metalloporphyrins in the Dye Formation Reaction of N, N-Diethylaniline with 4-Aminoantipyrine by Hydrogen Peroxide. / Saito, Yutaka; Mifune, Masaki; Nakashima, Suzuyo et al.

In: Chemical and Pharmaceutical Bulletin, Vol. 35, No. 2, 1987, p. 869-872.

Research output: Contribution to journal › Article › peer-review

Saito, Y, Mifune, M, Nakashima, S, Nakayama, H, Odo, J, Tanaka, Y, Chikuma, M & Tanaka, H 1987, 'Peroxidase-like Catalytic Activity of Anion-Exchange Resins Modified with Metalloporphyrins in the Dye Formation Reaction of N, N-Diethylaniline with 4-Aminoantipyrine by Hydrogen Peroxide', Chemical and Pharmaceutical Bulletin, vol. 35, no. 2, pp. 869-872. https://doi.org/10.1248/cpb.35.869

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abstract = "In an attempt to develop a practically useful mimesis of peroxidase, the peroxidase-like catalytic activity of anion exchange resins (Amberlite IRA 900) modified with manganese, cobalt, iron, copper and zinc complexes of some porphyrins was examined in terms of the accelerating effect on dye formation in the following reaction. The evaluation of the activity was carried out by comparison of the effect obtained by using the resins with that obtained by using peroxidase. peroxidase 4-aminoantipyrine+ N, N,-diethylaniline + 2H202 →Peroxidase quinoid dye + 4H20 Amberlite IRA 900 modified with manganese-tetrakis(sulfophenyl)porphine was found to be the best among the resins tested.",

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author = "Yutaka Saito and Masaki Mifune and Suzuyo Nakashima and Hiromi Nakayama and Junichi Odo and Yoshimasa Tanaka and Masahiko Chikuma and Hisashi Tanaka",

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AU - Mifune, Masaki

AU - Nakashima, Suzuyo

AU - Nakayama, Hiromi

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AU - Chikuma, Masahiko

AU - Tanaka, Hisashi

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KW - functionalization ion-exchange resin

KW - peroxidase mimesis

KW - peroxidase-like activity

KW - quinoid dye formation

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Peroxidase-like Catalytic Activity of Anion-Exchange Resins Modified with Metalloporphyrins in the Dye Formation Reaction of N, N-Diethylaniline with 4-Aminoantipyrine by Hydrogen Peroxide

Abstract

Keywords

ASJC Scopus subject areas

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