Peroxidase-like Catalytic Activity of Anion-Exchange Resins Modified with Metalloporphyrins in the Dye Formation Reaction of N, N-Diethylaniline with 4-Aminoantipyrine by Hydrogen Peroxide

Yutaka Saito, Masaki Mifune, Suzuyo Nakashima, Hiromi Nakayama, Junichi Odo, Yoshimasa Tanaka, Masahiko Chikuma, Hisashi Tanaka

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

In an attempt to develop a practically useful mimesis of peroxidase, the peroxidase-like catalytic activity of anion exchange resins (Amberlite IRA 900) modified with manganese, cobalt, iron, copper and zinc complexes of some porphyrins was examined in terms of the accelerating effect on dye formation in the following reaction. The evaluation of the activity was carried out by comparison of the effect obtained by using the resins with that obtained by using peroxidase. peroxidase 4-aminoantipyrine+ N, N,-diethylaniline + 2H202 →Peroxidase quinoid dye + 4H20 Amberlite IRA 900 modified with manganese-tetrakis(sulfophenyl)porphine was found to be the best among the resins tested.

Original languageEnglish
Pages (from-to)869-872
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume35
Issue number2
DOIs
Publication statusPublished - 1987

Fingerprint

Ampyrone
Metalloporphyrins
Anion Exchange Resins
Hydrogen Peroxide
Peroxidase
Catalyst activity
Coloring Agents
Manganese
Resins
Porphyrins
Cobalt
Zinc
Copper
Iron
N,N-diethylaniline

Keywords

  • functionalization ion-exchange resin
  • peroxidase mimesis
  • peroxidase-like activity
  • quinoid dye formation
  • resin modified metalloporphyrin

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

Cite this

Peroxidase-like Catalytic Activity of Anion-Exchange Resins Modified with Metalloporphyrins in the Dye Formation Reaction of N, N-Diethylaniline with 4-Aminoantipyrine by Hydrogen Peroxide. / Saito, Yutaka; Mifune, Masaki; Nakashima, Suzuyo; Nakayama, Hiromi; Odo, Junichi; Tanaka, Yoshimasa; Chikuma, Masahiko; Tanaka, Hisashi.

In: Chemical and Pharmaceutical Bulletin, Vol. 35, No. 2, 1987, p. 869-872.

Research output: Contribution to journalArticle

Saito, Yutaka ; Mifune, Masaki ; Nakashima, Suzuyo ; Nakayama, Hiromi ; Odo, Junichi ; Tanaka, Yoshimasa ; Chikuma, Masahiko ; Tanaka, Hisashi. / Peroxidase-like Catalytic Activity of Anion-Exchange Resins Modified with Metalloporphyrins in the Dye Formation Reaction of N, N-Diethylaniline with 4-Aminoantipyrine by Hydrogen Peroxide. In: Chemical and Pharmaceutical Bulletin. 1987 ; Vol. 35, No. 2. pp. 869-872.
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AU - Saito, Yutaka

AU - Mifune, Masaki

AU - Nakashima, Suzuyo

AU - Nakayama, Hiromi

AU - Odo, Junichi

AU - Tanaka, Yoshimasa

AU - Chikuma, Masahiko

AU - Tanaka, Hisashi

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