Abstract
In an attempt to develop a practically useful mimesis of peroxidase, the peroxidase-like catalytic activity of anion exchange resins (Amberlite IRA 900) modified with manganese, cobalt, iron, copper and zinc complexes of some porphyrins was examined in terms of the accelerating effect on dye formation in the following reaction. The evaluation of the activity was carried out by comparison of the effect obtained by using the resins with that obtained by using peroxidase. peroxidase 4-aminoantipyrine+ N, N,-diethylaniline + 2H202 →Peroxidase quinoid dye + 4H20 Amberlite IRA 900 modified with manganese-tetrakis(sulfophenyl)porphine was found to be the best among the resins tested.
| Original language | English |
|---|---|
| Pages (from-to) | 869-872 |
| Number of pages | 4 |
| Journal | Chemical and Pharmaceutical Bulletin |
| Volume | 35 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1987 |
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Keywords
- functionalization ion-exchange resin
- peroxidase mimesis
- peroxidase-like activity
- quinoid dye formation
- resin modified metalloporphyrin
ASJC Scopus subject areas
- Chemistry(all)
- Drug Discovery
Cite this
Peroxidase-like Catalytic Activity of Anion-Exchange Resins Modified with Metalloporphyrins in the Dye Formation Reaction of N, N-Diethylaniline with 4-Aminoantipyrine by Hydrogen Peroxide. / Saito, Yutaka; Mifune, Masaki; Nakashima, Suzuyo; Nakayama, Hiromi; Odo, Junichi; Tanaka, Yoshimasa; Chikuma, Masahiko; Tanaka, Hisashi.
In: Chemical and Pharmaceutical Bulletin, Vol. 35, No. 2, 1987, p. 869-872.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Peroxidase-like Catalytic Activity of Anion-Exchange Resins Modified with Metalloporphyrins in the Dye Formation Reaction of N, N-Diethylaniline with 4-Aminoantipyrine by Hydrogen Peroxide
AU - Saito, Yutaka
AU - Mifune, Masaki
AU - Nakashima, Suzuyo
AU - Nakayama, Hiromi
AU - Odo, Junichi
AU - Tanaka, Yoshimasa
AU - Chikuma, Masahiko
AU - Tanaka, Hisashi
PY - 1987
Y1 - 1987
N2 - In an attempt to develop a practically useful mimesis of peroxidase, the peroxidase-like catalytic activity of anion exchange resins (Amberlite IRA 900) modified with manganese, cobalt, iron, copper and zinc complexes of some porphyrins was examined in terms of the accelerating effect on dye formation in the following reaction. The evaluation of the activity was carried out by comparison of the effect obtained by using the resins with that obtained by using peroxidase. peroxidase 4-aminoantipyrine+ N, N,-diethylaniline + 2H202 →Peroxidase quinoid dye + 4H20 Amberlite IRA 900 modified with manganese-tetrakis(sulfophenyl)porphine was found to be the best among the resins tested.
AB - In an attempt to develop a practically useful mimesis of peroxidase, the peroxidase-like catalytic activity of anion exchange resins (Amberlite IRA 900) modified with manganese, cobalt, iron, copper and zinc complexes of some porphyrins was examined in terms of the accelerating effect on dye formation in the following reaction. The evaluation of the activity was carried out by comparison of the effect obtained by using the resins with that obtained by using peroxidase. peroxidase 4-aminoantipyrine+ N, N,-diethylaniline + 2H202 →Peroxidase quinoid dye + 4H20 Amberlite IRA 900 modified with manganese-tetrakis(sulfophenyl)porphine was found to be the best among the resins tested.
KW - functionalization ion-exchange resin
KW - peroxidase mimesis
KW - peroxidase-like activity
KW - quinoid dye formation
KW - resin modified metalloporphyrin
UR - http://www.scopus.com/inward/record.url?scp=0000880716&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0000880716&partnerID=8YFLogxK
U2 - 10.1248/cpb.35.869
DO - 10.1248/cpb.35.869
M3 - Article
AN - SCOPUS:0000880716
VL - 35
SP - 869
EP - 872
JO - Chemical and Pharmaceutical Bulletin
JF - Chemical and Pharmaceutical Bulletin
SN - 0009-2363
IS - 2
ER -