Permeability of alginate/sol-gel synthesized aminopropyl-silicate/alginate membrane templated by calcium-alginate gel

Shinji Sakai, Tsutomu Ono, Hiroyuki Ijima, Koei Kawakami

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

An alginate/aminopropyl-silicate/alginate membrane was prepared on calcium-alginate gel beads via electrostatic interaction and sol-gel processes. The effects of the chemical composition and the molecular weight (MW) of the core alginate on the permeability of the alginate/aminopropyl-silicate/alginate membrane were investigated for five different types of alginates. Our data shows that an immunoisolatable MW cut-off point was achieved for the membranes formed on the alginates, MW=7.0×104 with molar ratio of M/G (mannuronic acid to guluronic acid), M/G=1.30, MW=1.1×105 with M/G=1.30, and MW=7.0×104 with M/G=0.65. For these three membranes, the membrane templated by the alginate of MW=1.1×105 had a higher MW cut-off point than that templated by the alginate of MW=7.0×104. In addition, the MW cut-off point increased with an increase in the content of guluronic acid. The membranes formed on the alginates of MW=2.0×104 with M/G=1.30, and MW=7.0×104 with M/G=2.25 did not have an immunoisolatable MW cut-off point.

Original languageEnglish
Pages (from-to)183-189
Number of pages7
JournalJournal of Membrane Science
Volume205
Issue number1-2
DOIs
Publication statusPublished - Aug 1 2002
Externally publishedYes

Fingerprint

Silicates
Alginate
Polymethyl Methacrylate
Sol-gels
calcium
Calcium
Permeability
molecular weight
silicates
permeability
Gels
Molecular Weight
Molecular weight
gels
membranes
Membranes
Alginates
cut-off
acids
Acids

Keywords

  • Alginate
  • Immunoisolation membrane
  • Microcapsule-shaped bioartificial organ
  • Silicate
  • Sol-gel method

ASJC Scopus subject areas

  • Filtration and Separation
  • Polymers and Plastics

Cite this

Permeability of alginate/sol-gel synthesized aminopropyl-silicate/alginate membrane templated by calcium-alginate gel. / Sakai, Shinji; Ono, Tsutomu; Ijima, Hiroyuki; Kawakami, Koei.

In: Journal of Membrane Science, Vol. 205, No. 1-2, 01.08.2002, p. 183-189.

Research output: Contribution to journalArticle

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