Perioperative change of ionized magnesium concentration - Effect of blood transfusion-

O. Nagano, S. Iwadoh, Y. Sanagawa, Yoshimasa Takeda, M. Yokoyama, H. Katayama, M. Hirakawa

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Abstract

In order to evaluate the effect of intra-operative blood transfusion on post-operative decrease of ionized Mg (Mg 2+), we performed following studies. 1) We measured ionized Mg (Mg 2+), total Mg, ionized Ca (Ca 2+), total Ca and citrate before and after operation in 70 patients. 2) We evaluated the effect of citrate on Mg 2+ and Ca 2+ in vitro. 3) We also measured these values during blood transfusion in 8 patients. There was no significant difference between post-operative Mg 2+ of 45 patients without blood transfusion (0.49±0.07 mmol · l -1, % decrease from pre-operative value was 13.4±9.2%; mean±SD), and that of 25 patients with blood transfusion (0.48±0.09 mmol · l -1, 17.9±10.2%). Mean value of post- operative citrate concentration of patients with blood transfusion was 0.15±0.11 mmol · l -1, and this value decreased Mg 2+ about 2% in in vitro study. During blood transfusion, Mg 2+ (0.41±0.05 mmol · l -1) and ionized % (54.5±8.3%) decreased significantly just like Ca 2+ with elevated citrate concentration (0.95±0.59 mmol · l -1). In conclusion, intraoperative blood transfusion had minor effect on the post-operative decrease of Mg 2+, and the major cause was thought to be the dilution of extracellular fluid by Mg-free fluid administered during operation.

Original languageEnglish
Pages (from-to)627-633
Number of pages7
JournalJapanese Journal of Anesthesiology
Volume48
Issue number6
Publication statusPublished - 1999

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Blood Transfusion
Magnesium
Citric Acid
Extracellular Fluid

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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Nagano, O., Iwadoh, S., Sanagawa, Y., Takeda, Y., Yokoyama, M., Katayama, H., & Hirakawa, M. (1999). Perioperative change of ionized magnesium concentration - Effect of blood transfusion-. Japanese Journal of Anesthesiology, 48(6), 627-633.

Perioperative change of ionized magnesium concentration - Effect of blood transfusion-. / Nagano, O.; Iwadoh, S.; Sanagawa, Y.; Takeda, Yoshimasa; Yokoyama, M.; Katayama, H.; Hirakawa, M.

In: Japanese Journal of Anesthesiology, Vol. 48, No. 6, 1999, p. 627-633.

Research output: Contribution to journalArticle

Nagano, O, Iwadoh, S, Sanagawa, Y, Takeda, Y, Yokoyama, M, Katayama, H & Hirakawa, M 1999, 'Perioperative change of ionized magnesium concentration - Effect of blood transfusion-', Japanese Journal of Anesthesiology, vol. 48, no. 6, pp. 627-633.
Nagano, O. ; Iwadoh, S. ; Sanagawa, Y. ; Takeda, Yoshimasa ; Yokoyama, M. ; Katayama, H. ; Hirakawa, M. / Perioperative change of ionized magnesium concentration - Effect of blood transfusion-. In: Japanese Journal of Anesthesiology. 1999 ; Vol. 48, No. 6. pp. 627-633.
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abstract = "In order to evaluate the effect of intra-operative blood transfusion on post-operative decrease of ionized Mg (Mg 2+), we performed following studies. 1) We measured ionized Mg (Mg 2+), total Mg, ionized Ca (Ca 2+), total Ca and citrate before and after operation in 70 patients. 2) We evaluated the effect of citrate on Mg 2+ and Ca 2+ in vitro. 3) We also measured these values during blood transfusion in 8 patients. There was no significant difference between post-operative Mg 2+ of 45 patients without blood transfusion (0.49±0.07 mmol · l -1, {\%} decrease from pre-operative value was 13.4±9.2{\%}; mean±SD), and that of 25 patients with blood transfusion (0.48±0.09 mmol · l -1, 17.9±10.2{\%}). Mean value of post- operative citrate concentration of patients with blood transfusion was 0.15±0.11 mmol · l -1, and this value decreased Mg 2+ about 2{\%} in in vitro study. During blood transfusion, Mg 2+ (0.41±0.05 mmol · l -1) and ionized {\%} (54.5±8.3{\%}) decreased significantly just like Ca 2+ with elevated citrate concentration (0.95±0.59 mmol · l -1). In conclusion, intraoperative blood transfusion had minor effect on the post-operative decrease of Mg 2+, and the major cause was thought to be the dilution of extracellular fluid by Mg-free fluid administered during operation.",
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AU - Katayama, H.

AU - Hirakawa, M.

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