Perineuronal sulfated proteoglycans in the human brain are identical to Golgi's reticular coating

Takuro Murakami, Aiji Ohtsuka, Da Xun Piao

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Many neurons in the human somatosensory cortex (Area 7 of Brodmann) possess an intensely negative-charged surface coat consisting of perineuronal sulfated proteoglycans which were stained with cationic iron colloid. This surface coat was stained doubly with cationic iron colloid and Golgi's silver nitrate. The result indicates that the perineuronal sulfated proteoglycans are identical with Golgi's reticular coating, whose existence and nature have previously been controversial. The result also suggests that Golgi's silver nitrate stains the core proteins of proteoglycans.

Original languageEnglish
Pages (from-to)233-237
Number of pages5
JournalArchives of Histology and Cytology
Issue number3
Publication statusPublished - 1996


ASJC Scopus subject areas

  • Anatomy
  • Histology

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