Abstract
As our previous study has indicated, perineuronal proteoglycans in the adult mouse brain are associated with some collagenous molecules which can be stained with Gomori's ammoniacal silver and are resistant to hyaluronidase digestion. The present study demonstrated that these molecules are thoroughly digested with collagenase, and suggests that they represent a hyaluronic acid-binding domain of the ligand proteoglycans connecting the perineuronal proteoglycans and nerve cell surface glycoproteins.
| Original language | English |
|---|---|
| Pages (from-to) | 199-204 |
| Number of pages | 6 |
| Journal | Archives of Histology and Cytology |
| Volume | 62 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1999 |
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ASJC Scopus subject areas
- Anatomy
- Histology
Cite this
Perineuronal nets of proteoglycans in the adult mouse brain are digested by collagenase. / Murakami, Takuro; Murakami, Tetsuro; Su, W. D.; Ohtsuka, Aiji; Abe, Koji; Ninomiya, Yoshifumi.
In: Archives of Histology and Cytology, Vol. 62, No. 2, 1999, p. 199-204.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Perineuronal nets of proteoglycans in the adult mouse brain are digested by collagenase
AU - Murakami, Takuro
AU - Murakami, Tetsuro
AU - Su, W. D.
AU - Ohtsuka, Aiji
AU - Abe, Koji
AU - Ninomiya, Yoshifumi
PY - 1999
Y1 - 1999
N2 - As our previous study has indicated, perineuronal proteoglycans in the adult mouse brain are associated with some collagenous molecules which can be stained with Gomori's ammoniacal silver and are resistant to hyaluronidase digestion. The present study demonstrated that these molecules are thoroughly digested with collagenase, and suggests that they represent a hyaluronic acid-binding domain of the ligand proteoglycans connecting the perineuronal proteoglycans and nerve cell surface glycoproteins.
AB - As our previous study has indicated, perineuronal proteoglycans in the adult mouse brain are associated with some collagenous molecules which can be stained with Gomori's ammoniacal silver and are resistant to hyaluronidase digestion. The present study demonstrated that these molecules are thoroughly digested with collagenase, and suggests that they represent a hyaluronic acid-binding domain of the ligand proteoglycans connecting the perineuronal proteoglycans and nerve cell surface glycoproteins.
UR - http://www.scopus.com/inward/record.url?scp=0032973657&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032973657&partnerID=8YFLogxK
U2 - 10.1679/aohc.62.199
DO - 10.1679/aohc.62.199
M3 - Article
C2 - 10399544
AN - SCOPUS:0032973657
VL - 62
SP - 199
EP - 204
JO - Archives of Histology and Cytology
JF - Archives of Histology and Cytology
SN - 0914-9465
IS - 2
ER -