Perineuronal nets of proteoglycans in the adult mouse brain are digested by collagenase

Takuro Murakami; Tetsuro Murakami; W. D. Su; Aiji Ohtsuka; Koji Abe; Yoshifumi Ninomiya

doi:10.1679/aohc.62.199

Perineuronal nets of proteoglycans in the adult mouse brain are digested by collagenase

Takuro Murakami, Tetsuro Murakami, W. D. Su, Aiji Ohtsuka, Koji Abe, Yoshifumi Ninomiya

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

As our previous study has indicated, perineuronal proteoglycans in the adult mouse brain are associated with some collagenous molecules which can be stained with Gomori's ammoniacal silver and are resistant to hyaluronidase digestion. The present study demonstrated that these molecules are thoroughly digested with collagenase, and suggests that they represent a hyaluronic acid-binding domain of the ligand proteoglycans connecting the perineuronal proteoglycans and nerve cell surface glycoproteins.

Original language	English
Pages (from-to)	199-204
Number of pages	6
Journal	archives of histology and cytology
Volume	62
Issue number	2
DOIs	https://doi.org/10.1679/aohc.62.199
Publication status	Published - May 1999

ASJC Scopus subject areas

Histology

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AU - Murakami, Takuro

AU - Murakami, Tetsuro

AU - Su, W. D.

AU - Ohtsuka, Aiji

AU - Abe, Koji

AU - Ninomiya, Yoshifumi

PY - 1999/5

Y1 - 1999/5

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Perineuronal nets of proteoglycans in the adult mouse brain are digested by collagenase

Abstract

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