Percutaneous Radiofrequency Ablation of Lung Tumors Close to the Heart or Aorta

Evaluation of Safety and Effectiveness

Toshihiro Iguchi, Takao Hiraki, Hideo Gobara, Hidefumi Mimura, Hiroyasu Fujiwara, Nobuhisa Tajiri, Jun Sakurai, Kotaro Yasui, Hiroshi Date, Susumu Kanazawa

Research output: Contribution to journalArticle

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Abstract

Purpose: The authors retrospectively evaluated the safety and effectiveness of percutaneous radiofrequency ablation of lung tumors close to the heart or aorta. Materials and Methods: Forty-two tumors (mean diameter, 25 mm ± 16; range, 5-73 mm) located less than 10 mm from the heart or aorta were treated with radiofrequency ablation in 47 sessions. Lung tumors were classified into two groups according to their distance from the heart or aorta: group A (n = 27) comprised tumors at a distance of 1-9 mm; group B (n = 15) comprised contiguous tumors (distance, 0 mm). The safety and technique effectiveness of the procedure, defined as no evidence of local tumor progression, were evaluated. Results: Radiofrequency ablation was feasible for all the 42 tumors. Procedural complications included asymptomatic pleural effusion (n = 5), small pneumothorax (n = 11), pneumothorax that necessitated chest tube placement (n = 4), and lung abscess (n = 1). No complications related to the specific tumor location, such as the accidental insertion of the electrode into the heart or aorta, pericardial effusion, arrhythmia, or cardiac infarction, occurred. The overall primary technique effectiveness rate was 75.8%, 45.9%, and 45.9% at 6, 12, and 24 months, respectively. This rate in group A (94.7%, 69.3%, and 69.3% at 6, 12, and 24 months, respectively) was significantly (P <.001) higher than that in group B (42.9% and 8.6% at 6 and 12 months, respectively). Conclusions: Radiofrequency ablation of lung tumors close to the heart or aorta was safely performed. The local control of tumors contiguous to the heart or aorta was considerably lower compared with the tumors that were close but not contiguous to these structures.

Original languageEnglish
Pages (from-to)733-740
Number of pages8
JournalJournal of Vascular and Interventional Radiology
Volume18
Issue number6
DOIs
Publication statusPublished - Jun 2007

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Aorta
Safety
Lung
Neoplasms
Pneumothorax
Lung Abscess
Chest Tubes
Pericardial Effusion
Pleural Effusion
Infarction
Cardiac Arrhythmias
Electrodes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Percutaneous Radiofrequency Ablation of Lung Tumors Close to the Heart or Aorta : Evaluation of Safety and Effectiveness. / Iguchi, Toshihiro; Hiraki, Takao; Gobara, Hideo; Mimura, Hidefumi; Fujiwara, Hiroyasu; Tajiri, Nobuhisa; Sakurai, Jun; Yasui, Kotaro; Date, Hiroshi; Kanazawa, Susumu.

In: Journal of Vascular and Interventional Radiology, Vol. 18, No. 6, 06.2007, p. 733-740.

Research output: Contribution to journalArticle

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title = "Percutaneous Radiofrequency Ablation of Lung Tumors Close to the Heart or Aorta: Evaluation of Safety and Effectiveness",
abstract = "Purpose: The authors retrospectively evaluated the safety and effectiveness of percutaneous radiofrequency ablation of lung tumors close to the heart or aorta. Materials and Methods: Forty-two tumors (mean diameter, 25 mm ± 16; range, 5-73 mm) located less than 10 mm from the heart or aorta were treated with radiofrequency ablation in 47 sessions. Lung tumors were classified into two groups according to their distance from the heart or aorta: group A (n = 27) comprised tumors at a distance of 1-9 mm; group B (n = 15) comprised contiguous tumors (distance, 0 mm). The safety and technique effectiveness of the procedure, defined as no evidence of local tumor progression, were evaluated. Results: Radiofrequency ablation was feasible for all the 42 tumors. Procedural complications included asymptomatic pleural effusion (n = 5), small pneumothorax (n = 11), pneumothorax that necessitated chest tube placement (n = 4), and lung abscess (n = 1). No complications related to the specific tumor location, such as the accidental insertion of the electrode into the heart or aorta, pericardial effusion, arrhythmia, or cardiac infarction, occurred. The overall primary technique effectiveness rate was 75.8{\%}, 45.9{\%}, and 45.9{\%} at 6, 12, and 24 months, respectively. This rate in group A (94.7{\%}, 69.3{\%}, and 69.3{\%} at 6, 12, and 24 months, respectively) was significantly (P <.001) higher than that in group B (42.9{\%} and 8.6{\%} at 6 and 12 months, respectively). Conclusions: Radiofrequency ablation of lung tumors close to the heart or aorta was safely performed. The local control of tumors contiguous to the heart or aorta was considerably lower compared with the tumors that were close but not contiguous to these structures.",
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AU - Hiraki, Takao

AU - Gobara, Hideo

AU - Mimura, Hidefumi

AU - Fujiwara, Hiroyasu

AU - Tajiri, Nobuhisa

AU - Sakurai, Jun

AU - Yasui, Kotaro

AU - Date, Hiroshi

AU - Kanazawa, Susumu

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N2 - Purpose: The authors retrospectively evaluated the safety and effectiveness of percutaneous radiofrequency ablation of lung tumors close to the heart or aorta. Materials and Methods: Forty-two tumors (mean diameter, 25 mm ± 16; range, 5-73 mm) located less than 10 mm from the heart or aorta were treated with radiofrequency ablation in 47 sessions. Lung tumors were classified into two groups according to their distance from the heart or aorta: group A (n = 27) comprised tumors at a distance of 1-9 mm; group B (n = 15) comprised contiguous tumors (distance, 0 mm). The safety and technique effectiveness of the procedure, defined as no evidence of local tumor progression, were evaluated. Results: Radiofrequency ablation was feasible for all the 42 tumors. Procedural complications included asymptomatic pleural effusion (n = 5), small pneumothorax (n = 11), pneumothorax that necessitated chest tube placement (n = 4), and lung abscess (n = 1). No complications related to the specific tumor location, such as the accidental insertion of the electrode into the heart or aorta, pericardial effusion, arrhythmia, or cardiac infarction, occurred. The overall primary technique effectiveness rate was 75.8%, 45.9%, and 45.9% at 6, 12, and 24 months, respectively. This rate in group A (94.7%, 69.3%, and 69.3% at 6, 12, and 24 months, respectively) was significantly (P <.001) higher than that in group B (42.9% and 8.6% at 6 and 12 months, respectively). Conclusions: Radiofrequency ablation of lung tumors close to the heart or aorta was safely performed. The local control of tumors contiguous to the heart or aorta was considerably lower compared with the tumors that were close but not contiguous to these structures.

AB - Purpose: The authors retrospectively evaluated the safety and effectiveness of percutaneous radiofrequency ablation of lung tumors close to the heart or aorta. Materials and Methods: Forty-two tumors (mean diameter, 25 mm ± 16; range, 5-73 mm) located less than 10 mm from the heart or aorta were treated with radiofrequency ablation in 47 sessions. Lung tumors were classified into two groups according to their distance from the heart or aorta: group A (n = 27) comprised tumors at a distance of 1-9 mm; group B (n = 15) comprised contiguous tumors (distance, 0 mm). The safety and technique effectiveness of the procedure, defined as no evidence of local tumor progression, were evaluated. Results: Radiofrequency ablation was feasible for all the 42 tumors. Procedural complications included asymptomatic pleural effusion (n = 5), small pneumothorax (n = 11), pneumothorax that necessitated chest tube placement (n = 4), and lung abscess (n = 1). No complications related to the specific tumor location, such as the accidental insertion of the electrode into the heart or aorta, pericardial effusion, arrhythmia, or cardiac infarction, occurred. The overall primary technique effectiveness rate was 75.8%, 45.9%, and 45.9% at 6, 12, and 24 months, respectively. This rate in group A (94.7%, 69.3%, and 69.3% at 6, 12, and 24 months, respectively) was significantly (P <.001) higher than that in group B (42.9% and 8.6% at 6 and 12 months, respectively). Conclusions: Radiofrequency ablation of lung tumors close to the heart or aorta was safely performed. The local control of tumors contiguous to the heart or aorta was considerably lower compared with the tumors that were close but not contiguous to these structures.

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