Percutaneous Radiofrequency Ablation for Pulmonary Metastases from Colorectal Cancer: Midterm Results in 27 Patients

Takao Hiraki, Hideo Gobara, Tatsuhiko Iishi, Yoshifumi Sano, Toshihiro Iguchi, Hiroyasu Fujiwara, Nobuhisa Tajiri, Jun Sakurai, Hiroshi Date, Hidefumi Mimura, Susumu Kanazawa

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50 Citations (Scopus)

Abstract

Purpose: To retrospectively evaluate the midterm outcomes (eg, safety, local efficacy, and survival) after radiofrequency (RF) ablation for pulmonary metastases from colorectal cancer. Materials and Methods: Twenty-seven patients (19 men and eight women; mean age, 61.6 years) with 49 pulmonary metastases (mean long axis diameter, 1.5 cm) from colorectal cancer underwent 41 percutaneous computed tomography (CT)-guided RF ablation sessions. Follow-up examinations were performed with CT by using contrast medium administration in all patients; positron emission tomography was performed in five patients. The safety of the procedure, local tumor control, and patient survival were evaluated. Multiple variables were analyzed to determine prognostic factors. Results: Pneumothorax occurred after 20 of the 41 sessions (49%), three of which necessitated chest tube placement. A small pleural effusion was found after six of the 41 sessions (15%). No major hemorrhagic event was observed. None of the patients died due to the procedure. The median follow-up period was 20.1 months (range, 11.2-47.7 months). The primary and secondary technique effectiveness rates were 72% and 85%, respectively, at 1 year, 56% and 62% at 2 years, and 56% and 62% at 3 years. The overall survival rates after RF ablation were 96% at 1 year, 54% at 2 years, and 48% at 3 years. The presence of extrapulmonary metastasis was determined to be a prognostic factor (P = .001). Conclusions: The midterm outcomes of percutaneous RF ablation for colorectal pulmonary metastases appear promising. The presence of extrapulmonary metastasis had an adverse effect on survival after RF ablation.

Original languageEnglish
Pages (from-to)1264-1269
Number of pages6
JournalJournal of Vascular and Interventional Radiology
Volume18
Issue number10
DOIs
Publication statusPublished - Oct 1 2007

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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