Penostatins, novel cytotoxic metabolites from a Penicillium species separated from a green alga

Chika Takahashi, Atsushi Numata, Takeshi Yamada, Katsuhiko Minoura, Shoichi Enomoto, Katsuhiro Konishi, Misa Nakai, Chitose Matsuda, Kyosuke Nomoto

Research output: Contribution to journalArticlepeer-review

51 Citations (Scopus)

Abstract

Penostatins A (1), B (2), C (3) and D (4) have been isolated from a strain of Penicillium sp. originally separated from the marine alga Enteromorpha intestinalis, and their stereostructures have been established on the basis of spectral analyses. The compounds 1 ~ 3 exhibited significant cytotoxicity against cultured P388 cells.

Original languageEnglish
Pages (from-to)655-658
Number of pages4
JournalTetrahedron Letters
Volume37
Issue number5
DOIs
Publication statusPublished - Jan 29 1996

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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