Penostatins, novel cytotoxic metabolites from a Penicillium species separated from a green alga

Chika Takahashi, Atsushi Numata, Takeshi Yamada, Katsuhiko Minoura, Shoichi Enomoto, Katsuhiro Konishi, Misa Nakai, Chitose Matsuda, Kyosuke Nomoto

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Penostatins A (1), B (2), C (3) and D (4) have been isolated from a strain of Penicillium sp. originally separated from the marine alga Enteromorpha intestinalis, and their stereostructures have been established on the basis of spectral analyses. The compounds 1 ~ 3 exhibited significant cytotoxicity against cultured P388 cells.

Original languageEnglish
Pages (from-to)655-658
Number of pages4
JournalTetrahedron Letters
Volume37
Issue number5
DOIs
Publication statusPublished - Jan 29 1996
Externally publishedYes

Fingerprint

Chlorophyta
Penicillium
Cytotoxicity
Algae
Metabolites
Cultured Cells
penostatin A

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Takahashi, C., Numata, A., Yamada, T., Minoura, K., Enomoto, S., Konishi, K., ... Nomoto, K. (1996). Penostatins, novel cytotoxic metabolites from a Penicillium species separated from a green alga. Tetrahedron Letters, 37(5), 655-658. https://doi.org/10.1016/0040-4039(95)02225-2

Penostatins, novel cytotoxic metabolites from a Penicillium species separated from a green alga. / Takahashi, Chika; Numata, Atsushi; Yamada, Takeshi; Minoura, Katsuhiko; Enomoto, Shoichi; Konishi, Katsuhiro; Nakai, Misa; Matsuda, Chitose; Nomoto, Kyosuke.

In: Tetrahedron Letters, Vol. 37, No. 5, 29.01.1996, p. 655-658.

Research output: Contribution to journalArticle

Takahashi, C, Numata, A, Yamada, T, Minoura, K, Enomoto, S, Konishi, K, Nakai, M, Matsuda, C & Nomoto, K 1996, 'Penostatins, novel cytotoxic metabolites from a Penicillium species separated from a green alga', Tetrahedron Letters, vol. 37, no. 5, pp. 655-658. https://doi.org/10.1016/0040-4039(95)02225-2
Takahashi, Chika ; Numata, Atsushi ; Yamada, Takeshi ; Minoura, Katsuhiko ; Enomoto, Shoichi ; Konishi, Katsuhiro ; Nakai, Misa ; Matsuda, Chitose ; Nomoto, Kyosuke. / Penostatins, novel cytotoxic metabolites from a Penicillium species separated from a green alga. In: Tetrahedron Letters. 1996 ; Vol. 37, No. 5. pp. 655-658.
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