Abstract
New ring-opening reaction of thiazoline-azetidinones 1 to dithioazetidinones 2 was achieved with 2-benzothiazolyl disulfide in aqueous acidic media and its potentiality for the preparation of a variety of cephalosporins 3 from various thiazoline-azetidinones 1 is demonstrated.
| Original language | English |
|---|---|
| Pages (from-to) | 2017-2020 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 25 |
| Issue number | 19 |
| DOIs | |
| Publication status | Published - 1984 |
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ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
Cite this
Torii, S., Tanaka, H., Siroi, T., & Sasaoka, M. (1984). Penicillin-cephalosporin conversion X. New synthesis of dithioazetidinones from thiazoline-azetidinones. Tetrahedron Letters, 25(19), 2017-2020. https://doi.org/10.1016/S0040-4039(01)90101-7