Penicillin-cephalosporin conversion X. New synthesis of dithioazetidinones from thiazoline-azetidinones

Sigeru Torii, Hideo Tanaka, Takashi Siroi, Michio Sasaoka

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

New ring-opening reaction of thiazoline-azetidinones 1 to dithioazetidinones 2 was achieved with 2-benzothiazolyl disulfide in aqueous acidic media and its potentiality for the preparation of a variety of cephalosporins 3 from various thiazoline-azetidinones 1 is demonstrated.

Original languageEnglish
Pages (from-to)2017-2020
Number of pages4
JournalTetrahedron Letters
Volume25
Issue number19
DOIs
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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