Penicillin-cephalosporin conversion X. New synthesis of dithioazetidinones from thiazoline-azetidinones

Sigeru Torii; Hideo Tanaka; Takashi Siroi; Michio Sasaoka

doi:10.1016/S0040-4039(01)90101-7

Penicillin-cephalosporin conversion X. New synthesis of dithioazetidinones from thiazoline-azetidinones

Sigeru Torii, Hideo Tanaka, Takashi Siroi, Michio Sasaoka

Faculty of Engineering

Research output: Contribution to journal › Article

1 Citation (Scopus)

Abstract

New ring-opening reaction of thiazoline-azetidinones 1 to dithioazetidinones 2 was achieved with 2-benzothiazolyl disulfide in aqueous acidic media and its potentiality for the preparation of a variety of cephalosporins 3 from various thiazoline-azetidinones 1 is demonstrated.

Original language	English
Pages (from-to)	2017-2020
Number of pages	4
Journal	Tetrahedron Letters
Volume	25
Issue number	19
DOIs	https://doi.org/10.1016/S0040-4039(01)90101-7
Publication status	Published - 1984

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Penicillin-cephalosporin conversion X. New synthesis of dithioazetidinones from thiazoline-azetidinones",

abstract = "New ring-opening reaction of thiazoline-azetidinones 1 to dithioazetidinones 2 was achieved with 2-benzothiazolyl disulfide in aqueous acidic media and its potentiality for the preparation of a variety of cephalosporins 3 from various thiazoline-azetidinones 1 is demonstrated.",

author = "Sigeru Torii and Hideo Tanaka and Takashi Siroi and Michio Sasaoka",

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AU - Torii, Sigeru

AU - Tanaka, Hideo

AU - Siroi, Takashi

AU - Sasaoka, Michio

PY - 1984

Y1 - 1984

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AB - New ring-opening reaction of thiazoline-azetidinones 1 to dithioazetidinones 2 was achieved with 2-benzothiazolyl disulfide in aqueous acidic media and its potentiality for the preparation of a variety of cephalosporins 3 from various thiazoline-azetidinones 1 is demonstrated.

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