Pd- and Cu-catalyzed one-pot multicomponent synthesis of hetero α,α′-dimers of heterocycles

Takahiko Murata, Masahito Murai, Yuji Ikeda, Koji Miki, Kouichi Ohe

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25 Citations (Scopus)

Abstract

A novel palladium- and copper-catalyzed one-pot multicomponent synthesis of hetero α,α′-dimers of heterocycles via Sonogashira coupling and double cyclization cascade involving imine formation has been developed. This reaction cascade proceeded under mild conditions, providing a powerful synthetic tool for the assembly of π-conjugated systems with a combination of palladium-catalyzed post-direct C-H bond arylations.

Original languageEnglish
Pages (from-to)2296-2299
Number of pages4
JournalOrganic Letters
Volume14
Issue number9
DOIs
Publication statusPublished - May 4 2012

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ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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