Patients with brain metastases after lung cancer surgery

Toshiya Bessho, Shinichiro Miyoshi, Shinji Maebeya, Takaomi Suzuma, Issei Hirai, Hirokazu Tanino, Tatsuya Yoshimasu, Junji Arimoto, Yasuaki Naito, Yuji Uematsu

Research output: Contribution to journalArticle

Abstract

Thirty five patients with brain metastases after lung resection for primary lung cancer were retrospectively reviewed. Of there, 19 patients (54.3%) had a solitary brain metastasis and 16 patients (45.7%) had multiple brain metastases. Eighteen (51.4%) of the 35 patients underwent brain operations. The five-year survival rate and median survival time (MST) were 20.0% and 9.5 months in patients with brain operations. In patients without brain operations, the MST was 4 months and no patients survived more than 13 months. The analysis of the several prognostic factors in the patients with brain operations revealed that only no metastases to other organs than brain at brain surgery significantly prolonged the survival. Five (27.8%) of 18 patients with brain surgery survived more than 3 years. All had a solitary brain metastasis without metastases to other organs. Four of them underwent operations from two to four times for brain metastasis. Such an aggressive surgical treatment may permit long-term survival in patients with a single brain metastasis.

Original languageEnglish
Pages (from-to)205-213
Number of pages9
JournalJapanese Journal of Lung Cancer
Volume38
Issue number3
Publication statusPublished - Jun 1998
Externally publishedYes

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Lung Neoplasms
Neoplasm Metastasis
Brain
Survival
Survival Rate
Lung

Keywords

  • Brain metastasis
  • Lung cancer
  • Surgical treatment

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine

Cite this

Bessho, T., Miyoshi, S., Maebeya, S., Suzuma, T., Hirai, I., Tanino, H., ... Uematsu, Y. (1998). Patients with brain metastases after lung cancer surgery. Japanese Journal of Lung Cancer, 38(3), 205-213.

Patients with brain metastases after lung cancer surgery. / Bessho, Toshiya; Miyoshi, Shinichiro; Maebeya, Shinji; Suzuma, Takaomi; Hirai, Issei; Tanino, Hirokazu; Yoshimasu, Tatsuya; Arimoto, Junji; Naito, Yasuaki; Uematsu, Yuji.

In: Japanese Journal of Lung Cancer, Vol. 38, No. 3, 06.1998, p. 205-213.

Research output: Contribution to journalArticle

Bessho, T, Miyoshi, S, Maebeya, S, Suzuma, T, Hirai, I, Tanino, H, Yoshimasu, T, Arimoto, J, Naito, Y & Uematsu, Y 1998, 'Patients with brain metastases after lung cancer surgery', Japanese Journal of Lung Cancer, vol. 38, no. 3, pp. 205-213.
Bessho T, Miyoshi S, Maebeya S, Suzuma T, Hirai I, Tanino H et al. Patients with brain metastases after lung cancer surgery. Japanese Journal of Lung Cancer. 1998 Jun;38(3):205-213.
Bessho, Toshiya ; Miyoshi, Shinichiro ; Maebeya, Shinji ; Suzuma, Takaomi ; Hirai, Issei ; Tanino, Hirokazu ; Yoshimasu, Tatsuya ; Arimoto, Junji ; Naito, Yasuaki ; Uematsu, Yuji. / Patients with brain metastases after lung cancer surgery. In: Japanese Journal of Lung Cancer. 1998 ; Vol. 38, No. 3. pp. 205-213.
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