Patients’ perspectives of rheumatoid arthritis treatment: a questionnaire survey for the 2020 update of the Japan college of rheumatology clinical practice guidelines

Masayo Kojima, Mieko Hasegawa, Shintaro Hirata, Hiromu Ito, Yuko Kaneko, Mitsumasa Kishimoto, Masataka Kohno, Toshihisa Kojima, Isao Matsushita, Masaaki Mori, Akio Morinobu, Atsuko Murashima, Keiichiro Nishida, Yohei Seto, Yasumori Sobue, Takahiko Sugihara, Eiichi Tanaka, Takeo Nakayama, Yutaka Kawahito, Masayoshi Harigai

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: This study aimed to evaluate patients’ opinions regarding their rheumatoid arthritis (RA) therapy and to reflect the patients’ perspectives in the 2020 update of the Japan College of Rheumatology clinical practice guidelines. Methods: A self-administered questionnaire was mailed to 1600 members of the Japan Rheumatology Friendship Association, who were randomly selected by age and prefecture. Results: A total of 1156 patients returned the questionnaire (response rate, 72.3%; mean age, 63.0 ± 11.9 years). Those who reported having discussed their treatment goals with their doctors (450 respondents, 38.9%) were more likely to be satisfied with their current medical care (odds ratio, 7.13; 95% CI 4.72–10.8) compared with those who had not discussed their goals nor had them explained (287 respondents, 24.8%). The benefits exceeded the adverse effects for all pharmacotherapy (methotrexate, corticosteroids, conventional synthetic antirheumatic drugs, biological agents, Janus kinase inhibitor, and anti-RANKL antibodies). However, while 74.2% of the respondents using biological agents perceived that ‘the favorable aspects outweighed the unfavorable aspects,’ most of those taking anti-RANKL antibodies (69.2%) felt uncertain. Conclusions: The questionnaire successfully collected information regarding patients’ perceptions regarding their therapy. Further implementation of treat-to-target is necessary in Japan to improve patient satisfaction.

Original languageEnglish
JournalModern Rheumatology
DOIs
Publication statusAccepted/In press - 2021
Externally publishedYes

Keywords

  • Clinical guidelines
  • patient
  • rheumatoid arthritis
  • satisfaction
  • treat-to-target

ASJC Scopus subject areas

  • Rheumatology

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