Pathological findings of infraorbital nerve enlargement in igG4-related ophthalmic disease

Yuka Sogabe, Katsuya Miyatani, Rieko Goto, Gengo Ishii, Kohichi Ohshima, Yasuharu Sato

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Purpose: We report a case of bilateral infraorbital nerve enlargement (IONE) associated with immunoglobulin (Ig)G4-related ophthalmic disease and describe the associated histopathologic findings. Case: An otherwise healthy 59-year-old man presented with bilateral exophthalmos and right visual disturbance. Orbital magnetic resonance imaging showed bilateral IONE and a soft tissue mass in the right orbit. Excisional biopsy in the left infraorbital canal was performed. Histopathologic assessment revealed igG4-related disease involving the epineurium of the infraorbital nerve. The patient received systemic steroid therapy, to which he responded well. Conclusion: IONE in igG4-related ophthalmic disease is due to igG4-related disease involving the epineurium.

Original languageEnglish
Pages (from-to)511-514
Number of pages4
JournalJapanese Journal of Ophthalmology
Volume56
Issue number5
DOIs
Publication statusPublished - Sep 2012

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Eye Diseases
Immunoglobulin G
Peripheral Nerves
Exophthalmos
Orbit
Immunoglobulins
Steroids
Magnetic Resonance Imaging
Biopsy
Therapeutics

Keywords

  • IgG4-related disease
  • Infraorbital nerve
  • Nerve tumor
  • Orbital tumor
  • Trigeminal nerve lesion

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Pathological findings of infraorbital nerve enlargement in igG4-related ophthalmic disease. / Sogabe, Yuka; Miyatani, Katsuya; Goto, Rieko; Ishii, Gengo; Ohshima, Kohichi; Sato, Yasuharu.

In: Japanese Journal of Ophthalmology, Vol. 56, No. 5, 09.2012, p. 511-514.

Research output: Contribution to journalArticle

Sogabe, Yuka ; Miyatani, Katsuya ; Goto, Rieko ; Ishii, Gengo ; Ohshima, Kohichi ; Sato, Yasuharu. / Pathological findings of infraorbital nerve enlargement in igG4-related ophthalmic disease. In: Japanese Journal of Ophthalmology. 2012 ; Vol. 56, No. 5. pp. 511-514.
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