TY - JOUR
T1 - Pathological and molecular diagnosis of the 2013 African swine fever outbreak in Lusaka, Zambia
AU - Yabe, John
AU - Hamambulu, Pharaoh
AU - Simulundu, Edgar
AU - Ogawa, Hirohito
AU - Kajihara, Masahiro
AU - Mori-Kajihara, Akina
AU - Changula-Chitanga, Katendi
AU - Mwase, Max
AU - Mweemba-Muwowo, Mutinta
AU - Chambaro, Herman Moses
AU - Mataa, Liywalii
AU - Hang’ombe, Bernard
AU - Namangala, Bonniface
AU - Fandamu, Paul
AU - Sawa, Hirofumi
AU - Takada, Ayato
AU - Higashi, Hideaki
AU - Mweene, Aaron Simanyengwe
N1 - Funding Information:
This work was supported by the Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) and Japan Science and Technology Agency (JST)/Japan International Cooperation Agency (JICA) within the framework of the Science and Technology Research Partnership for Sustainable Development (SATREPS).
Publisher Copyright:
© 2014, Springer Science+Business Media Dordrecht.
PY - 2014/2
Y1 - 2014/2
N2 - African swine fever (ASF) is a highly contagious and fatal hemorrhagic viral disease of domestic pigs. The disease is widespread in sub-Saharan Africa and has repeatedly been introduced into other continents. The current study describes the diagnostic investigations of a hemorrhagic disease that was reported in pigs in Lusaka (October 2013), Zambia. Necropsy, histopathology, and molecular diagnosis using polymerase chain reaction and sequence analysis confirmed the disease to be ASF. The sequences obtained showed high similarity to previously isolated ASF viruses. Consistent surveillance and rapid diagnosis of the disease is recommended to prevent future outbreaks and economic losses as there is currently no vaccine against the disease.
AB - African swine fever (ASF) is a highly contagious and fatal hemorrhagic viral disease of domestic pigs. The disease is widespread in sub-Saharan Africa and has repeatedly been introduced into other continents. The current study describes the diagnostic investigations of a hemorrhagic disease that was reported in pigs in Lusaka (October 2013), Zambia. Necropsy, histopathology, and molecular diagnosis using polymerase chain reaction and sequence analysis confirmed the disease to be ASF. The sequences obtained showed high similarity to previously isolated ASF viruses. Consistent surveillance and rapid diagnosis of the disease is recommended to prevent future outbreaks and economic losses as there is currently no vaccine against the disease.
KW - African swine fever
KW - PCR
KW - Pathology
KW - Zambia
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U2 - 10.1007/s11250-014-0732-0
DO - 10.1007/s11250-014-0732-0
M3 - Article
C2 - 25535151
AN - SCOPUS:84925511561
SN - 0049-4747
VL - 47
SP - 459
EP - 463
JO - Tropical Animal Health and Production
JF - Tropical Animal Health and Production
IS - 2
ER -
