Pasteurella multocida multiple intrapelvic abscesses in a young woman with uterine cervical cancer

Keigo Kimura, Hideharu Hagiya, Norihisa Yamamoto, Hisao Yoshida, Yukihiro Akeda, Isao Nishi, Kazunori Tomono

Research output: Contribution to journalArticle

Abstract

Pasteurella multocida, a zoonotic pathogen in humans, is known to be associated with skin and soft tissue infections following animal bites, but rarely causes visceral infections. We report a case of P. multocida-associated multiple intrapelvic abscesses in a young woman with uterine cervical cancer. A 29-year-old unmarried woman was referred to us because of prolonged high fever accompanying abdominal pain with muscular guarding. She had a domestic cat but denied of any bites or scratches before that. Computed tomography demonstrated ascites and multiple abscesses around her uterus. Her condition did not improve with an initial treatment with flomoxef, clindamycin, and azithromycin. Further, we performed percutaneous pus drainage and switched the antimicrobial therapy to a combination of piperacillin/tazobactam and minocycline for 10 days. Although P. multocida was isolated from vaginal culture, no organisms were isolated from the pus culture. However, further investigation with specimen-direct 16S rDNA analysis diagnosed P. multocida as possibly a single pathogen responsible for the intrapelvic infection. After taking oral levofloxacin for two weeks, no recurrence was reported. Although P. multocida is known as an animal-related pathogen, it can transmit to humans without apparent bites or scratches. The present case illustrates that P. multocida can cause intrapelvic abscess as a result of ascending genital infection.

Original languageEnglish
Pages (from-to)197-199
Number of pages3
JournalJournal of Infection and Chemotherapy
Volume25
Issue number3
DOIs
Publication statusPublished - Mar 2019
Externally publishedYes

Fingerprint

Pasteurella multocida
Uterine Cervical Neoplasms
Abscess
Bites and Stings
Suppuration
Infection
Levofloxacin
Soft Tissue Infections
Minocycline
Azithromycin
Clindamycin
Zoonoses
Ribosomal DNA
Ascites
Abdominal Pain
Uterus
Drainage
Cats
Fever
Tomography

Keywords

  • Ascending infection
  • Cervical cancer
  • Genital infection
  • Pasteurella multocida
  • Pelvic inflammatory disease
  • Zoonotic infection

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Pasteurella multocida multiple intrapelvic abscesses in a young woman with uterine cervical cancer. / Kimura, Keigo; Hagiya, Hideharu; Yamamoto, Norihisa; Yoshida, Hisao; Akeda, Yukihiro; Nishi, Isao; Tomono, Kazunori.

In: Journal of Infection and Chemotherapy, Vol. 25, No. 3, 03.2019, p. 197-199.

Research output: Contribution to journalArticle

Kimura, Keigo ; Hagiya, Hideharu ; Yamamoto, Norihisa ; Yoshida, Hisao ; Akeda, Yukihiro ; Nishi, Isao ; Tomono, Kazunori. / Pasteurella multocida multiple intrapelvic abscesses in a young woman with uterine cervical cancer. In: Journal of Infection and Chemotherapy. 2019 ; Vol. 25, No. 3. pp. 197-199.
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