Palmitoylation-dependent membrane localization of the rice resistance protein pit is critical for the activation of the small GTPase OsRac1

Yoji Kawano, Tadashi Fujiwara, Ai Yao, Yusuke Housen, Keiko Hayashi, Ko Shimamoto

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Background: Mechanisms and significance of immune receptor R protein localization to specific compartments remain unknown. Results: Palmitoylation-deficient R protein Pit fails to induce GTPase OsRac1 activation at the plasma membrane, thereby compromising Pit-mediated disease resistance. Conclusion: Palmitoylation-dependent membrane localization of Pit contributes to Pit-mediated disease resistance through OsRac1 activation. Significance: Elucidating relationships between R protein localization and activation of downstream molecules improve our understanding of plant immunity.

Original languageEnglish
Pages (from-to)19079-19088
Number of pages10
JournalJournal of Biological Chemistry
Volume289
Issue number27
DOIs
Publication statusPublished - Jul 4 2014
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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