Abstract
A series of unsymmetrical diarylethynes have been synthesized by the copper-catalyzed cross-coupling reaction of alkynylboronates with aryl iodides in high to excellent yields under palladium-free conditions. A wide range of substrates bearing an electron-donating or an electron-withdrawing substituent on the aromatic ring are compatible with this reaction.
Original language | English |
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Pages (from-to) | 518-521 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 54 |
Issue number | 6 |
DOIs | |
Publication status | Published - Feb 6 2013 |
Keywords
- Alkynylboronates
- Copper
- Sonogashira-Hagihara coupling
- Stephens-Castro reaction
- Suzuki-Miyaura coupling
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry