Abstract
Boron delivery: C-H borylation at the ortho-position of aromatic compounds is promoted by the treatment of 2-phenylpyridine, or its derivatives, with 9-borabicyclo[3.3.1]nonane in the presence of a palladium catalyst. This reaction proceeds at room temperature and can be conducted without the palladium catalyst at higher temperatures. In both cases, the regioselectivity is controlled by Lewis acid-base interaction between the boron and nitrogen atoms.
Original language | English |
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Pages (from-to) | 4431-4434 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 52 |
Issue number | 16 |
DOIs | |
Publication status | Published - Apr 15 2013 |
Keywords
- Lewis acid
- Lewis base
- borylation
- palladium
- regioselectivity
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)