Palladium-Catalyzed Decarbonylative Alkylation of Acyl Fluorides

Liyan Fu, Qiang Chen, Zhenhua Wang, Yasushi Nishihara

    Research output: Contribution to journalArticlepeer-review

    17 Citations (Scopus)

    Abstract

    Palladium-catalyzed decarbonylative alkylation reactions of acyl fluorides have been developed using alkylboranes having β-hydrogens. A wide range of functional groups were well tolerated, even at the high temperature required for decarbonylation. This protocol provides a diverse C(sp2)-C(sp3) bond formation via a highly efficient decarbonylative process. The hemilabile bidentate ligand DPPE plays a crucial role for retardation of the undesired β-hydride elimination.

    Original languageEnglish
    JournalACS Applied Materials and Interfaces
    DOIs
    Publication statusAccepted/In press - 2020

    ASJC Scopus subject areas

    • Materials Science(all)

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