Abstract
11-Oxo-Δ8-tetrahydrocannabinol was oxidized to Δ8-tetrahydrocannabinol-11-oic acid by mouse hepatic microsomes. The oxygenation mechanism in the reaction was confirmed by the incorporation of oxygen-18 from molecular oxygen into Δ8-tetrahydrocannabinol-11-oic acid. The oxygenation of aldehyde to carboxylic acid represents a novel mechanism in biological oxidation of aldehyde to carboxylic acid.
| Original language | English |
|---|---|
| Pages (from-to) | 779-782 |
| Number of pages | 4 |
| Journal | Biochemical and Biophysical Research Communications |
| Volume | 153 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Jun 16 1988 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Biochemistry
- Biophysics
- Molecular Biology
Cite this
Oxygenation mechanism in the oxidation of xenobiotic aldehyde to carboxylic acid by mouse hepatic microsomes. / Yamamoto, Ikuo; Watanabe, Kazuhito; Narimatsu, Shizuo; Yoshimura, Hidetoshi.
In: Biochemical and Biophysical Research Communications, Vol. 153, No. 2, 16.06.1988, p. 779-782.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Oxygenation mechanism in the oxidation of xenobiotic aldehyde to carboxylic acid by mouse hepatic microsomes
AU - Yamamoto, Ikuo
AU - Watanabe, Kazuhito
AU - Narimatsu, Shizuo
AU - Yoshimura, Hidetoshi
PY - 1988/6/16
Y1 - 1988/6/16
N2 - 11-Oxo-Δ8-tetrahydrocannabinol was oxidized to Δ8-tetrahydrocannabinol-11-oic acid by mouse hepatic microsomes. The oxygenation mechanism in the reaction was confirmed by the incorporation of oxygen-18 from molecular oxygen into Δ8-tetrahydrocannabinol-11-oic acid. The oxygenation of aldehyde to carboxylic acid represents a novel mechanism in biological oxidation of aldehyde to carboxylic acid.
AB - 11-Oxo-Δ8-tetrahydrocannabinol was oxidized to Δ8-tetrahydrocannabinol-11-oic acid by mouse hepatic microsomes. The oxygenation mechanism in the reaction was confirmed by the incorporation of oxygen-18 from molecular oxygen into Δ8-tetrahydrocannabinol-11-oic acid. The oxygenation of aldehyde to carboxylic acid represents a novel mechanism in biological oxidation of aldehyde to carboxylic acid.
UR - http://www.scopus.com/inward/record.url?scp=0023927661&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023927661&partnerID=8YFLogxK
U2 - 10.1016/S0006-291X(88)81163-X
DO - 10.1016/S0006-291X(88)81163-X
M3 - Article
C2 - 2838024
AN - SCOPUS:0023927661
VL - 153
SP - 779
EP - 782
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
SN - 0006-291X
IS - 2
ER -