Abstract
11-Oxo-Δ8-tetrahydrocannabinol was oxidized to Δ8-tetrahydrocannabinol-11-oic acid by mouse hepatic microsomes. The oxygenation mechanism in the reaction was confirmed by the incorporation of oxygen-18 from molecular oxygen into Δ8-tetrahydrocannabinol-11-oic acid. The oxygenation of aldehyde to carboxylic acid represents a novel mechanism in biological oxidation of aldehyde to carboxylic acid.
| Original language | English |
|---|---|
| Pages (from-to) | 779-782 |
| Number of pages | 4 |
| Journal | Biochemical and Biophysical Research Communications |
| Volume | 153 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Jun 16 1988 |
ASJC Scopus subject areas
- Biophysics
- Biochemistry
- Molecular Biology
- Cell Biology
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Cite this
Yamamoto, I., Watanabe, K., Narimatsu, S., & Yoshimura, H. (1988). Oxygenation mechanism in the oxidation of xenobiotic aldehyde to carboxylic acid by mouse hepatic microsomes. Biochemical and Biophysical Research Communications, 153(2), 779-782. https://doi.org/10.1016/S0006-291X(88)81163-X