Translated title of the contribution: Osteosarcoma in siblings - A case report

F. Danckwerth, P. Wuisman, J. Ritter, S. Blasius, H. Jurgens, T. Ozaki, W. Winkelmann

Research output: Contribution to journalArticle

4 Citations (Scopus)


With a brother and sister, osteosarcoma developed at the age of 11 and 14 respectively. With both there was no previous retinoblastoma or other bone disease with a proclivity to develop osteosarcoma. We discuss possible explanations for familial aggregation of osteosarcoma, citing external or genetic factors. We suggest that it is the retinoblastoma gene RB and the tumor suppressor gene p53 which play an important part in the development of osteosarcoma.

Translated title of the contributionOsteosarcoma in siblings - A case report
Original languageGerman
Pages (from-to)298-301
Number of pages4
JournalKlinische Padiatrie
Issue number5
Publication statusPublished - Jan 1 1995
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Danckwerth, F., Wuisman, P., Ritter, J., Blasius, S., Jurgens, H., Ozaki, T., & Winkelmann, W. (1995). OSTEOSARKOM BEI ZWEI GESCHWISTERN - EINE KASUISTISCHE DARSTELLUNG. Klinische Padiatrie, 207(5), 298-301.