Osmotic shrinkage of cells of Synechocystis sp. PCC 6803 by water efflux via aquaporins regulates osmostress-inducible gene expression

Alexey Shapiguzov, Alexander A. Lyukevich, Suleyman Allakhverdiev, Tatiana V. Sergeyenko, Iwane Suzuki, Norio Murata, Dmitry A. Los

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Abstract

Osmotic stress causes water molecules to efflux from cells through the cytoplasmic membrane. This study reveals that targeted mutation of the aqpZ gene, encoding an aquaporin water channel protein, in the cyanobacterium Synechocystis sp. PCC 6803 prevents the osmotic shrinkage of cells, suggesting that it is the water channel rather than the lipid bilayer that is primarily responsible for water transition through the membrane of this organism. The observations suggest that the aquaporin-mediated shrinkage of the Synechocystis cells plays an important role in changes of gene expression in response to hyperosmotic stress.

Original languageEnglish
Pages (from-to)447-455
Number of pages9
JournalMicrobiology
Volume151
Issue number2
DOIs
Publication statusPublished - Feb 1 2005
Externally publishedYes

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ASJC Scopus subject areas

  • Microbiology

Cite this

Shapiguzov, A., Lyukevich, A. A., Allakhverdiev, S., Sergeyenko, T. V., Suzuki, I., Murata, N., & Los, D. A. (2005). Osmotic shrinkage of cells of Synechocystis sp. PCC 6803 by water efflux via aquaporins regulates osmostress-inducible gene expression. Microbiology, 151(2), 447-455. https://doi.org/10.1099/mic.0.27530-0