Osmotic shrinkage of cells of Synechocystis sp. PCC 6803 by water efflux via aquaporins regulates osmostress-inducible gene expression

Alexey Shapiguzov, Alexander A. Lyukevich, Suleyman I. Allakhverdiev, Tatiana V. Sergeyenko, Iwane Suzuki, Norio Murata, Dmitry A. Los

    Research output: Contribution to journalArticlepeer-review

    50 Citations (Scopus)

    Abstract

    Osmotic stress causes water molecules to efflux from cells through the cytoplasmic membrane. This study reveals that targeted mutation of the aqpZ gene, encoding an aquaporin water channel protein, in the cyanobacterium Synechocystis sp. PCC 6803 prevents the osmotic shrinkage of cells, suggesting that it is the water channel rather than the lipid bilayer that is primarily responsible for water transition through the membrane of this organism. The observations suggest that the aquaporin-mediated shrinkage of the Synechocystis cells plays an important role in changes of gene expression in response to hyperosmotic stress.

    Original languageEnglish
    Pages (from-to)447-455
    Number of pages9
    JournalMicrobiology
    Volume151
    Issue number2
    DOIs
    Publication statusPublished - Feb 2005

    ASJC Scopus subject areas

    • Microbiology

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