Orthotopic neobladder reconstruction in elderly bladder cancer patients

Takashi Saika, Bunzo Suyama, Tadashi Murata, Daisuke Manabe, Takushi Kurashige, Yasutomo Nasu, Tomoyasu Tsushima, Hiromi Kumon

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Background: We compared the clinical results of orthotopic neobladder reconstruction in elderly patients and those in younger patients retrospectively in order to verify whether age is a critical factor in selecting a method of urinary diversion. Methods: Following radical cystectomy for bladder cancer, 12 patients aged 75 or older and 17 patients under 75 who underwent orthotopic neobladder reconstruction between January 1992 and May 1999 were investigated in this study. The authors TS and BS were among the surgeons who performed operations for all cases. Of the 12 elderly patients, orthotopic neobladders were constructed according to Hautmann's method in nine cases, Studer's method in one case and Reddy's method in two cases. Of the 17 younger patients, these methods were employed in 12, one and four cases, respectively. Operative procedure, early and late complications, prognosis, continence and voiding pattern were investigated in these patients. Results: The follow-up periods for elderly and younger groups ranged from 21.3 to 82.7 months and from 8.8 to 94.2 months, respectively. No difference in operation time, amount of bleeding or postoperative length of hospitalization was observed between elderly and younger patients. The rates of early complications in elderly and younger patients were 41.7% and 35.3%, respectively. Late complication rates were 33.3% and 47.1%, respectively. The difference in these complication rates was not statistically significant. One of the elderly and two of the younger patients had local recurrence and metastasis postoperatively. Those three patients had died of their bladder cancer. No statistically significant difference between groups was recognized in either cause-specific survival or overall survival, nor was there such a difference in relation to micturition/continence. Conclusion: Based on these results, we believe that because age is not a critical factor in the selection of urinary diversion method, neobladder reconstruction following cystectomy for bladder cancer is indicated in elderly patients. As stoma management is difficult for the patients, we consider orthotopic neobladder reconstruction to be the method of choice if the patients' general physical condition allows.

Original languageEnglish
Pages (from-to)533-538
Number of pages6
JournalInternational Journal of Urology
Volume8
Issue number10
DOIs
Publication statusPublished - 2001

Fingerprint

Urinary Bladder Neoplasms
Urinary Diversion
Cystectomy
Bleeding Time
Survival
Urination
Operative Surgical Procedures
Hospitalization
Neoplasm Metastasis

Keywords

  • Bladder carcinoma
  • Elderly patients
  • Orthotopic neobladder

ASJC Scopus subject areas

  • Urology

Cite this

Orthotopic neobladder reconstruction in elderly bladder cancer patients. / Saika, Takashi; Suyama, Bunzo; Murata, Tadashi; Manabe, Daisuke; Kurashige, Takushi; Nasu, Yasutomo; Tsushima, Tomoyasu; Kumon, Hiromi.

In: International Journal of Urology, Vol. 8, No. 10, 2001, p. 533-538.

Research output: Contribution to journalArticle

Saika, T, Suyama, B, Murata, T, Manabe, D, Kurashige, T, Nasu, Y, Tsushima, T & Kumon, H 2001, 'Orthotopic neobladder reconstruction in elderly bladder cancer patients', International Journal of Urology, vol. 8, no. 10, pp. 533-538. https://doi.org/10.1046/j.1442-2042.2001.00367.x
Saika, Takashi ; Suyama, Bunzo ; Murata, Tadashi ; Manabe, Daisuke ; Kurashige, Takushi ; Nasu, Yasutomo ; Tsushima, Tomoyasu ; Kumon, Hiromi. / Orthotopic neobladder reconstruction in elderly bladder cancer patients. In: International Journal of Urology. 2001 ; Vol. 8, No. 10. pp. 533-538.
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AU - Suyama, Bunzo

AU - Murata, Tadashi

AU - Manabe, Daisuke

AU - Kurashige, Takushi

AU - Nasu, Yasutomo

AU - Tsushima, Tomoyasu

AU - Kumon, Hiromi

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N2 - Background: We compared the clinical results of orthotopic neobladder reconstruction in elderly patients and those in younger patients retrospectively in order to verify whether age is a critical factor in selecting a method of urinary diversion. Methods: Following radical cystectomy for bladder cancer, 12 patients aged 75 or older and 17 patients under 75 who underwent orthotopic neobladder reconstruction between January 1992 and May 1999 were investigated in this study. The authors TS and BS were among the surgeons who performed operations for all cases. Of the 12 elderly patients, orthotopic neobladders were constructed according to Hautmann's method in nine cases, Studer's method in one case and Reddy's method in two cases. Of the 17 younger patients, these methods were employed in 12, one and four cases, respectively. Operative procedure, early and late complications, prognosis, continence and voiding pattern were investigated in these patients. Results: The follow-up periods for elderly and younger groups ranged from 21.3 to 82.7 months and from 8.8 to 94.2 months, respectively. No difference in operation time, amount of bleeding or postoperative length of hospitalization was observed between elderly and younger patients. The rates of early complications in elderly and younger patients were 41.7% and 35.3%, respectively. Late complication rates were 33.3% and 47.1%, respectively. The difference in these complication rates was not statistically significant. One of the elderly and two of the younger patients had local recurrence and metastasis postoperatively. Those three patients had died of their bladder cancer. No statistically significant difference between groups was recognized in either cause-specific survival or overall survival, nor was there such a difference in relation to micturition/continence. Conclusion: Based on these results, we believe that because age is not a critical factor in the selection of urinary diversion method, neobladder reconstruction following cystectomy for bladder cancer is indicated in elderly patients. As stoma management is difficult for the patients, we consider orthotopic neobladder reconstruction to be the method of choice if the patients' general physical condition allows.

AB - Background: We compared the clinical results of orthotopic neobladder reconstruction in elderly patients and those in younger patients retrospectively in order to verify whether age is a critical factor in selecting a method of urinary diversion. Methods: Following radical cystectomy for bladder cancer, 12 patients aged 75 or older and 17 patients under 75 who underwent orthotopic neobladder reconstruction between January 1992 and May 1999 were investigated in this study. The authors TS and BS were among the surgeons who performed operations for all cases. Of the 12 elderly patients, orthotopic neobladders were constructed according to Hautmann's method in nine cases, Studer's method in one case and Reddy's method in two cases. Of the 17 younger patients, these methods were employed in 12, one and four cases, respectively. Operative procedure, early and late complications, prognosis, continence and voiding pattern were investigated in these patients. Results: The follow-up periods for elderly and younger groups ranged from 21.3 to 82.7 months and from 8.8 to 94.2 months, respectively. No difference in operation time, amount of bleeding or postoperative length of hospitalization was observed between elderly and younger patients. The rates of early complications in elderly and younger patients were 41.7% and 35.3%, respectively. Late complication rates were 33.3% and 47.1%, respectively. The difference in these complication rates was not statistically significant. One of the elderly and two of the younger patients had local recurrence and metastasis postoperatively. Those three patients had died of their bladder cancer. No statistically significant difference between groups was recognized in either cause-specific survival or overall survival, nor was there such a difference in relation to micturition/continence. Conclusion: Based on these results, we believe that because age is not a critical factor in the selection of urinary diversion method, neobladder reconstruction following cystectomy for bladder cancer is indicated in elderly patients. As stoma management is difficult for the patients, we consider orthotopic neobladder reconstruction to be the method of choice if the patients' general physical condition allows.

KW - Bladder carcinoma

KW - Elderly patients

KW - Orthotopic neobladder

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