Origin of the Enhanced Reactivity in the ortho C–H Borylation of Benzaldehydes with BBr3

Ken Yamazaki, Supriya Rej, Yusuke Ano, Naoto Chatani

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

The metal-free ortho C–H borylation of benzaldehyde derivatives using a transient imine directing group was recently developed by our group, providing an efficient strategy for the synthesis of organoboron reagents. Herein, we report on an extensive investigation of the reaction mechanism using density functional theory (DFT) calculations.

Original languageEnglish
Pages (from-to)213-217
Number of pages5
JournalOrganic Letters
Volume24
Issue number1
DOIs
Publication statusPublished - Jan 14 2022
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Origin of the Enhanced Reactivity in the ortho C–H Borylation of Benzaldehydes with BBr3'. Together they form a unique fingerprint.

Cite this