TY - JOUR
T1 - Optical chromatography
T2 - Size determination by eluting particles
AU - Makihara, Jun
AU - Kaneta, Takashi
AU - Imasaka, Totaro
N1 - Funding Information:
This research is supported by Grants-in-Aid for Scientific Research from the Ministry of Education of Japan. We thank Dr Michael R. Shortreed for helpful discussions.
Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 1999/3
Y1 - 1999/3
N2 - A new method for the determination of particle size was developed using optical chromatography. After separating polystyrene particles, the laser power was gradually reduced, permitting the elution of small to large particles. Particle size was calculated from the laser power when the particle was eluted with a medium flow. This approach is more accurate than the technique previously reported because there is no need to determine the position of the beam waist. Advantages of the new approach are discussed theoretically and experimentally. The precision in size determination was improved by a factor of 3.3, i.e. the standard deviation in the measurement was reduced from 10 to 3% for 1 μm beads by replacing optical chromatography with the present method.
AB - A new method for the determination of particle size was developed using optical chromatography. After separating polystyrene particles, the laser power was gradually reduced, permitting the elution of small to large particles. Particle size was calculated from the laser power when the particle was eluted with a medium flow. This approach is more accurate than the technique previously reported because there is no need to determine the position of the beam waist. Advantages of the new approach are discussed theoretically and experimentally. The precision in size determination was improved by a factor of 3.3, i.e. the standard deviation in the measurement was reduced from 10 to 3% for 1 μm beads by replacing optical chromatography with the present method.
KW - Laser
KW - Optical chromatography
KW - Radiation pressure
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U2 - 10.1016/S0039-9140(98)00272-0
DO - 10.1016/S0039-9140(98)00272-0
M3 - Article
C2 - 18967495
AN - SCOPUS:0032956149
VL - 48
SP - 551
EP - 557
JO - Talanta
JF - Talanta
SN - 0039-9140
IS - 3
ER -