One-pot substitution-rearrangement reaction of 2-chloroglycidic ester: Effective protocol for the preparation of 3-arylsulfenyl-2-keto ester

Takuzo Komiyama, Yutaka Takaguchi, Sadao Tsuboi

Research output: Contribution to journalArticle

Abstract

The one-pot substitution-rearrangement reaction of 2-chloroglycidic ester is reported. Treatment of 2-chloroglycidic ester with sodium arylthiolate at room temperature results in the formation of 3-arylsulfenyl-2-keto ester in excellent to good yields.

Original languageEnglish
Pages (from-to)265-269
Number of pages5
JournalSynthetic Communications
Volume36
Issue number3
DOIs
Publication statusPublished - Jan 1 2006

Keywords

  • 2-Chloroglycidic ester
  • Darzens condensation
  • Dichloroacetate
  • Substitution-rearrangement reaction

ASJC Scopus subject areas

  • Organic Chemistry

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