One-Flask Synthesis of Sulfides from Alcohols and Alkyl Halides Using Benzoxazoline-2-thione

Yasuo Takeuchi, Keiko Sakagawa, Masumi Kubo, Masatoshi Yamato

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The synthesis of sulfides from alcohols and benzoxazoline-2-thione (I) was studied to establish its generality and the mechanism of the reaction. A one-flask synthesis of sulfides from alcohols was developed. According to this procedure, various sulfides were prepared without the use of ill-smelling thiols. Moreover, partial sulfenylation of diols to give sulfenyl alcohols was achieved.

Original languageEnglish
Pages (from-to)1323-1327
Number of pages5
JournalChemical and Pharmaceutical Bulletin
Volume34
Issue number3
DOIs
Publication statusPublished - 1986

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Thiones
Sulfides
Alcohols
Sulfhydryl Compounds

Keywords

  • benzoxazoline-2-thione
  • one-flask synthesis
  • partial sulfenylation
  • sulfenyl alcohol
  • sulfide

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

Cite this

One-Flask Synthesis of Sulfides from Alcohols and Alkyl Halides Using Benzoxazoline-2-thione. / Takeuchi, Yasuo; Sakagawa, Keiko; Kubo, Masumi; Yamato, Masatoshi.

In: Chemical and Pharmaceutical Bulletin, Vol. 34, No. 3, 1986, p. 1323-1327.

Research output: Contribution to journalArticle

Takeuchi, Yasuo ; Sakagawa, Keiko ; Kubo, Masumi ; Yamato, Masatoshi. / One-Flask Synthesis of Sulfides from Alcohols and Alkyl Halides Using Benzoxazoline-2-thione. In: Chemical and Pharmaceutical Bulletin. 1986 ; Vol. 34, No. 3. pp. 1323-1327.
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